All patients (n = 173) | R group (n = 129) | Control group (n = 44) | P value | |
---|---|---|---|---|
Bacteraemia | 65 (38) | 45 (35) | 20 (45) | 0.211 |
Septic shock | 35 (20) | 24 (18) | 11 (25) | |
Sepsis without shock | 24 (13) | 15 (11) | 9 (20) | |
No sepsis | 6 (3) | 6 (4) | 0 (0) | |
Infection site | ||||
Respiratory tract | 54 (31) | 41 (32) | 13 (30) | |
Urinary tract | 15 (9) | 12 (9) | 3 (7) | |
Catheter-related bloodstream | 7 (4) | 7 (5) | 0 (0) | |
Surgical site | 3 (2) | 2 (2) | 1 (2) | |
Clostridioides difficile | 0 (0) | 0 (0) | 0 (0) | |
Abdomen | 20 (12) | 13 (10) | 7 (16) | |
Central nervous system | 3 (2) | 2 (2) | 1 (2) | |
Other | 21 (12) | 16 (12) | 5 (11) | |
None | 50 (29) | 36 (28) | 14 (32) | |
Empiric antimicrobial administration | 141 (81) | 108 (83) | 33 (75) | 0.198 |
De-escalation | 59 (34) | 44 (34) | 15 (34) | 0.998 |
Other treatment in ICU | ||||
Intubation | 45 (26) | 33 (26) | 12 (27) | 0.825 |
Tracheostomy | 47 (27) | 37 (29) | 10 (23) | 0.443 |
Thoracic drainage | 24 (14) | 23 (18) | 1 (2) | 0.010 |
IPPV | 125 (72) | 88 (68) | 37 (84) | 0.042 |
NPPV | 10 (6) | 8 (6) | 2 (5) | 0.510 |
HFNC | 28 (16) | 20 (16) | 8 (18) | 0.677 |
CV | 59 (34) | 44 (34) | 15 (34) | 0.998 |
PICC | 26 (15) | 20 (16) | 6 (14) | 0.765 |
RRT | 41 (24) | 29 (22) | 12 (27) | 0.519 |
IABP | 20 (12) | 12 (9) | 8 (18) | 0.112 |
ECMO | 11 (6) | 9 (7) | 2 (5) | 0.437 |
TTM | 13 (8) | 7 (5) | 6 (14) | 0.078 |
Nutrition | ||||
EN | 76 (44) | 57 (44) | 19 (43) | 0.908 |
TPN | 18 (10) | 17 (13) | 1 (2) | 0.030 |
Number of days in the ICU | 10 (6–16) | 11 (6–19) | 10 (7–15) | 0.239 |
Number of days in the hospital | 48 (25–81) | 49 (25–82) | 43 (29–71) | 0.475 |
Ventilator-free days | 22 (5–27) | 22 (1–28) | 22 (11–26) | 0.836 |
28-day mortality | 31 (18) | 23 (18) | 8 (18) | 0.958 |
Discharge route-no. (%) | 0.556 | |||
Death | 50 (29) | 39 (30) | 11 (25) | |
Transferred to another hospital | 71 (41) | 54 (42) | 17 (39) | |
Discharged home | 52 (30) | 36 (28) | 16 (36) | |
HAI after ICU discharge | ||||
CDI (test n = 37) | 3 (2) | 3 (2) | 0 (0) | 0.412 |
Candidemia | 8 (5) | 8 (6) | 0 (0) | 0.090 |