Patient and ward related risk factors in a multi-ward nosocomial outbreak of COVID-19: Outbreak investigation and matched case–control study

Table 4 Independent risk factors for nosocomial COVID-19 from multivariate analysis

Variables	aIRR	95%CI	P value
Age	1.04	1.00–1.08	0.073
Underlying disease
Fluid/electrolyte disorders	3.82	1.62–9.02	0.002
Other neurological disorders	2.66	1.32–5.38	0.006
Medications
Days on diuretic	1.05	0.95–1.15	0.331
Days on immunosuppressive agents	1.39	1.06–1.83	0.018
Elixhauser score (AHRQ)	0.97	0.93–1.01	0.132
Abnormal lymphocyte	1.38	0.75–2.55	0.302
Percent of exposure on multi-bedded room
0–50% of time	Reference	Reference	Reference
> 50% of time	3.21	1.47–7.02	0.003

AHRQ agency for healthcare research and quality, CI confidence interval, aIRR adjusted incidence rate ratio
*Age, neurological disorders, fluid/electrolyte disorders, Elixhauser score, lymphocyte levels, activity, days spent on diuretics, days spent on immunosuppressive agents, and time spent on single bed and/or multi-bed rooms from univariate analysis were included in multivariate analysis. Activity was removed due to missing data, and of the variables capturing room use, only the percent of exposure in a multi-bed room was included due to heavy multicollinearity between these variables

ISSN: 2047-2994