Table 1 Characteristics of healthcare professional participants by serologic status
Variable | All Participants | Seropositive | Seronegative | p valuea |
|---|---|---|---|---|
N (%) | N (%) | N (%) | ||
Total N | 654 | 87 | 567 | Â |
Invitation cohort criteriab | ||||
 Occupational health visit | 273 (41.7) | 52 (59.8) | 166 (29.3) |  < 0.001 |
 Designated COVID-19 unit | 275 (42.0) | 31 (35.6) | 244 (43.0) | 0.19 |
 Non-COVID-19 unit (control) | 247 (37.8) | 36 (41.4) | 211 (37.2) | 0.46 |
 COVID-19 HCP-outbreak unit | 272 (41.6) | 46 (52.9) | 226 (39.9) | 0.02 |
 COVID-19 non-HCP-outbreak unit | 198 (30.3) | 27 (31.0) | 171 (30.2) | 0.86 |
Age (mean, SD) | 40 | 41 (47.1) | 40 (7.1) | 0.24 |
Male | 181 (27.7) | 27 (31.0) | 154 (27.2) | 0.42 |
Racec | ||||
 White | 174 (26.6) | 21 (24.1) | 153 (27.0) | 0.23 |
 Asian | 310 (47.4) | 39 (44.8) | 271 (47.8) |  |
 Black | 10 (1.5) | 2 (2.3) | 10 (1.8) |  |
 Other | 131 (20.0) | 17 (19.5) | 46 (8.1) |  |
Latino ethnicity | 101 (15.4) | 21 (24.1) | 80 (14.1) | 0.02 |
Socioeconomic status | ||||
 % Living in zipcodes where 10% or more have income below poverty line | 189 (28.9) | 27 (31.0) | 162 (28.6) | 0.64 |
 % Living in zipcodes where 80% or more have income below median household income | 237 (36.2) | 38 (43.7) | 199 (35.1) | 0.12 |
 % Living in zipcodes where owner-occupied household is less than 50% | 350 (53.5) | 54 (62.1) | 296 (52.2) | 0.09 |
 % Living in zipcodes where 25% or more live in a house with 1.5 or more occupants per room | 312 (47.7) | 52 (59.8) | 260 (45.9) | 0.02 |
 % Living in zipcodes where 50% households live in structures containing ≥ 5 units | 307 (46.9) | 42 (48.3) | 265 (46.7) | 0.79 |
Comorbidities (Any) | 141 (21.6) | 21 (24.1) | 120 (21.2) | 0.53 |
HCP role | ||||
 Registered nurse | 382 (58.4) | 53 (60.9) | 329 (58.0) | 0.12 |
 Nurse aide | 47 (7.2) | 12 (13.8) | 35 (6.2) |  |
 Physical/occupational therapist | 12 (1.8) | 2 (2.3) | 10 (1.8) |  |
 Respiratory therapist | 8 (1.2) | 1 (1.1) | 7 (1.2) |  |
 Physician | 99 (15.1) | 7 (8.0) | 92 (16.2) |  |
 Environmental services | 12 (1.8) | 1 (1.1) | 11 (1.9) |  |
 Other-direct patient care | 33 (5.0) | 2 (2.3) | 31 (5.5) |  |
 Not direct Pt care | 61 (9.3) | 9 (10.3) | 52 (9.2) |  |
COVID-19 patient care (Any)—Ehr reviewd | 276 (42.2) | 35 (40.2) | 241 (42.5) | 0.69 |
COVID-19 patient care—self-reportc | 355 (54.3) | 41 (47.1) | 314 (55.4) | 0.35 |
Aerosol generating procedurec | 97 (14.8) | 8 (9.2) | 89 (15.7) | 0.11 |
Works in ICUc | 153 (23.4) | 19 (21.8) | 134 (23.6) | 0.71 |
PCR results | ||||
 Positive | 54 (8.3) | 41 (47.1) | 13 (2.3) |  < 0.01 |
 Negative | 245 (37.5) | 19 (21.8) | 226 (39.9) |  |
 Unknown | 355 (54.3) | 27 (31.0) | 328 (57.8) |  |
Any COVID-19 symptom on self-reportc | 395 (60.4) | 62 (71.3) | 333 (58.7) |  < 0.01 |
No symptom reported | 230 (35.2) | 17 (19.5) | 213 (37.6) | Â |
Symptom type | ||||
 Non febrile illness | 222 (33.9) | 19 (21.8) | 203 (35.8) | 0.01 |
 Fever | 173 (26.5) | 43 (49.4) | 130 (22.9) |  < 0.01 |
 Fatigue | 234 (35.8) | 49 (56.3) | 185 (32.6) |  < 0.01 |
 Chills | 172 (26.3) | 46 (52.9) | 126 (22.2) |  < 0.01 |
 Myalgia | 197 (30.1) | 47 (54.0) | 150 (26.5) |  < 0.01 |
 Congestion | 298 (45.6) | 42 (48.3) | 256 (45.1) | 0.30 |
 Cough | 224 (34.3) | 37 (42.5) | 187 (33.0) | 0.03 |
 Loss of smell | 58 (8.9) | 30 (34.5) | 28 (4.9) |  < 0.01 |
 Shortness of breath | 106 (16.2) | 21 (24.1) | 85 (15.0) | 0.02 |
Days between symptoms and serology sample collection | ||||
 < 14 days | 30 (4.6) | 4 (4.6) | 26 (4.6) | 0.74 |
 15–29 days | 58 (8.9) | 10 (11.5) | 48 (8.5) | 0.69 |
 30–44 days | 17 (2.6) | 7 (8.0) | 10 (1.8) |  < 0.01 |
 45–59 days | 107 (16.4) | 23 (26.4) | 84 (14.8) | 0.04 |
 60–74 days | 13 (2.0) | 2 (2.3) | 11 (1.9) | 0.67 |
 ≥ 75 days | 169 (25.8) | 15 (17.2) | 154 (27.2) |  < 0.01 |