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Table 2 Indications for linezolid use. Data from the national point prevalence surveys 2011 and 2016. Data comparison of the two surveys

From: Linezolid use in German acute care hospitals: results from two consecutive national point prevalence surveys

Indication Variable Site of infection Number (percentage) p-value
PPS 2011 PPS 2016
All Total   119 (100) 255 (100) n.a.
Treatment (CI + LI + HI) Total   104 (87.4) 232 (91.0) 0.29
Site of infection (CI+ LI+ HI) All 104 (100) 232 (100)  
Bacteremia 10 (9.6) 27 (11.6) 0.38 (a)
Non-laboratory confirmed systemic infection 9 (8.7) 18 (7.8)
Bone/Joint infection 10 (9.6) 28 (12.1)
Skin/Soft tissue infection 21 (20.2) 55 (23.7)
Intraabdominal infection 5 (4.8) 23 (9.9)
Lower respiratory tract infection 27 (26.0) 42 (18.1)
Urinary tract infection 4 (3.8) 12 (5.2)
Other/Not specified 18 (17.3) 27 (11.6)
Treatment CI + LI Total   43 (36.1) 103 (40.4) 0.44
Site of infection (CI + LI) All 43 (100) 103 (100)  
Bacteremia 3 (7.0) 9 (8.7) 0.21 (a)
Non-laboratory confirmed systemic infection 4 (9.3) 5 (4.9)
Bone/Joint infection 4 (9.3) 11 (10.7)
Skin/Soft tissue infection 8 (18.6) 28 (27.2)
Intraabdominal infection 0 (0) 11 (10.7)
Lower respiratory infection 13 (30.2) 19 (18.4)
Urinary tract infection 2 (4.7) 6 (5.8)
Other/Not specified 9 (20.9) 14 (13.6)
Treatment HI Total   61 (51.3) 129 (50.6) 0.90
Site of infection (HI) All 61 (100) 129 (100)  
Bacteremia 7 (11.5) 18 (14.0) 0.94 (a)
Non-laboratory confirmed systemic infection 5 (8.2) 13 (10.1)
Bone/Joint infection 6 (9.8) 17 (13.2)
Skin/Soft tissue infection 13 (21.3) 27 (20.9)
Intraabdominal infection 5 (8.2) 12 (9.3)
Lower respiratory infection 14 (23.0) 23 (17.8)
Urinary tract infection 2 (3.3) 6 (4.7)
Other/Not specified 9 (14.8) 13 (10.1)
Other/Unknown    15 (12.6) 23 (9.0) 0.29
  1. Except where specified otherwise, p-values were calculated using Chi-squared test. Abbreviations: PPS point prevalence survey, CI community-acquired infection, LI infection acquired in long-term care, HI hospital-acquired infection, n.a. not applicable; (a) p-values were calculated for all listed sites of infection collectively using R by C tables