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Table 3 Univariate and multivariate analysis of the risk factors identified. All those with statistically significant Odds Ratios, at 95% confidence, are in bold

From: Antimicrobial susceptibility against metronidazole and carbapenem in clinical anaerobic isolates from Pakistan

 

Metronidazole resistance as outcome (n = 189)

Univariate analysis

Multivariate analysis

Clinical characteristics

OR (95% CI)

P Value

OR(95% CI)

P Value

Prolonged hospital stayb (≥ 7 days of hospital admission)

1.1 (0.5–2.5)

0.869

0.6 (0.2–1.7)

0.381

Age group (< 18 years as reference)

 

0.338

  

18–60 years

2.6 (0.7–9.0)

0.144

  

> 60 years

2.5 (0.6–10.7)

0.214

  

Female (Male as reference)

0.5 (0.2–1.2)

0.128

  

Organisms (Clostridium species as reference)

 

0.876

  

Bacteroides fragilis

0.6 (0.06–5.1)

0.611

  

Bacteroides other than fragilis

1.2 (0.5–3.0)

0.662

  

Othersa

1.016 (0.3–3.1)

0.978

  

Diabetes Mellitus

0.3 (0.06–1.3)

0.119

  

Malignancy/transplant

5.6 (1.7–17.9)

0.003

6.3(1.7–23.3)

0.005

Dialysis

4.2(0.2–68.5)

0.315

  

Bacteremia

2.3 (1.0–5.1)

0.041

2.1 (0.9–4.7)

0.089

Skin and soft tissue infection

0.6 (0.2–1.3)

0.181

  

Head and neck infections

0.4 (0.09–2.0)

0.302

  

Intraabdominal infections

1.1 (0.5–2.4)

0.739

  

Respiratory tract infections

2.1 (0.4–11.9)

0.399

  

Genitourinary infections

0.5 (0.1–2.4)

0.402

  

Expired

2.5 (0.7–9.0)

0.161

  
  1. a “Other” category includes Fusobacterium species, Cutibacterium species, Prevotella, Bifidobacterium, Eggerthella lenta
  2. bprimary exposure