| |
Parameters
|
Total
|
2011
|
2012
|
2013
|
2014
|
2015
|
2016
|
p-value
|
|
No of pts. (%)
|
No of pts. (%)
|
No of pts. (%)
|
No of pts. (%)
|
No of pts. (%)
|
No of pts. (%)
|
| |
Patients, total
|
2038
|
313 (100%)
|
350 (100%)
|
361 (100%)
|
341 (100%)
|
326 (100%)
|
347 (100%)
|
1.000
|
|
Children
|
345 (16.9%)
|
52 (16.6%)
|
57 (16.3%)
|
58 (16.1%)
|
65 (19.1%)
|
42 (12.9%)
|
71 (20.5%)
|
0.315
|
|
Male gender
|
1020 (50%)
|
154 (49.2%)
|
184 (52.6%)
|
186 (51.5%)
|
168 (49.3%)
|
164 (50.3%)
|
164 (47.3%)
|
0.976
|
|
Diagnosis
|
Brain trauma
|
255 (12.5%)
|
43 (13.7%)
|
54 (15.4%)
|
51 (14.1%)
|
41 (12.0%)
|
28 (8.6%)
|
38 (11.0%)
|
0.192
|
|
Brain tumor
|
1271 (62.4%)
|
185 (59.1%)
|
221 (63.1%)
|
240 (66.5%)
|
200 (58.7%)
|
209 (64.1%)
|
216 (62.2%)
|
0.911
|
|
Congenital disorders
|
23 (1.1%)
|
4 (1.3%)
|
5 (1.4%)
|
3 (0.8%)
|
7 (2.1%)
|
2 (0.6%)
|
2 (0.6%)
|
0.436
|
|
Vascular brain diseases
|
454 (22.3%)
|
77 (24.6%)
|
60 (17.1%)
|
63 (17.5%)
|
89 (26.1%)
|
80 (24.5%)
|
85 (24.5%)
|
0.066
|
|
Other diseases
|
29 (1.4%)
|
3 (1.0%)
|
10 (2.9%)
|
4 (1.1%)
|
4 (1.2%)
|
4 (1.2%)
|
4 (1.2%)
|
0.302
|
|
Surgeries
|
Craniotomy
|
1537 (75.4%)
|
230 (73.5%)
|
261 (74.6%)
|
279 (77.3%)
|
262 (76.8%)
|
245 (75.2%)
|
260 (74.9%)
|
0.998
|
|
INSD
|
650 (31.9%)
|
101 (32.3%)
|
130 (37.1%)
|
124 (34.3%)
|
112 (32.8%)
|
94 (28.8%)
|
89 (25.6%)
|
0.227
|
|
Endovascular surgery
|
194 (9.5%)
|
31 (9.9%)
|
37 (10.6%)
|
26 (7.2%)
|
40 (11.7%)
|
25 (7.7%)
|
35 (10.1%)
|
0.407
|
|
EETS
|
87 (4.3%)
|
13 (4.2%)
|
15 (4.3%)
|
15 (4.2%)
|
14 (4.1%)
|
15 (4.6%)
|
15 (4.3%)
|
1.000
|
|
Spinal surgery
|
4 (0.2%)
|
1 (0.3%)
|
0 (0.0%)
|
0 (0.0%)
|
0 (0.0%)
|
2 (0.6%)
|
1 (0.3%)
|
0.377
|
|
Other surgeries
|
873 (42.8%)
|
151 (48.2%)
|
161 (46.0%)
|
156 (43.2%)
|
146 (42.8%)
|
127 (39.0%)
|
132 (38.0%)
|
0.523
|
|
Outcomes
|
Recovery
|
80 (3.9%)
|
15 (4.8%)
|
14 (4.0%)
|
14 (3.9%)
|
19 (5.6%)
|
9 (2.8%)
|
9 (2.6%)
|
0.365
|
|
Positive dynamics
|
934 (45.8%)
|
133 (42.5%)
|
153 (43.7%)
|
170 (47.1%)
|
159 (46.6%)
|
150 (46.0%)
|
169 (48.7%)
|
0.934
|
|
No dynamics
|
210 (10.3%)
|
34 (10.9%)
|
41 (11.7%)
|
37 (10.2%)
|
30 (8.8%)
|
29 (8.9%)
|
39 (11.2%)
|
0.818
|
|
Negative dynamics
|
505 (24.8%)
|
81 (25.9%)
|
67 (19.1%)
|
78 (21.6%)
|
92 (27.0%)
|
96 (29.4%)
|
91 (26.2%)
|
0.153
|
|
Death
|
307 (15%)
|
50 (16.0%)
|
75 (21.4%)
|
62 (17.2%)
|
41 (12.0%)
|
41 (12.6%)
|
38 (11.0%)
|
0.009
|
| | |
Median [Q1;Q3]
|
Median [Q1;Q3]
|
Median [Q1;Q3]
|
Median [Q1;Q3]
|
Median [Q1;Q3]
|
Median [Q1;Q3]
|
Median [Q1;Q3]
|
p-value
|
| |
Age, years
|
46 [26.0; 59.0]
|
44 [25.0; 57.0]
|
44 [25.0; 58.0]
|
47 [26.0; 60.0]
|
44 [25.0; 57.0]
|
50 [30.0; 59.75]
|
48 [24.5; 60.5]
|
0.099
|
|
CCI score
|
3 [2.0; 5.0]
|
3 [2.0; 4.0]
|
3 [2.0; 5.0]
|
3 [2.0; 5.0]
|
3 [2.0; 4.0]
|
3 [2.0; 5.0]
|
3 [2.0; 4.0]
|
1.000
|
|
Length of stay in ICU, days
|
10 [6.0; 22.0]
|
13 [7.0; 27.0]
|
12 [6.0; 25.0]
|
10 [6.0; 24.0]
|
8 [6.0; 22.0]
|
9 [6.0; 22.0]
|
8 [5.0; 17.0]
|
0.010
|
- Abbreviations: INSD Implantation of neurosurgical devices, EETS Endoscopic endonasal transsphenoidal surgery, CCI Charlson comorbidity index
