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Table 1 Baseline characteristics of the study population by years

From: Implementing an infection control and prevention program decreases the incidence of healthcare-associated infections and antibiotic resistance in a Russian neuro-ICU

  Parameters Total 2011 2012 2013 2014 2015 2016 p-value
No of pts. (%) No of pts. (%) No of pts. (%) No of pts. (%) No of pts. (%) No of pts. (%)
  Patients, total 2038 313 (100%) 350 (100%) 361 (100%) 341 (100%) 326 (100%) 347 (100%) 1.000
Children 345 (16.9%) 52 (16.6%) 57 (16.3%) 58 (16.1%) 65 (19.1%) 42 (12.9%) 71 (20.5%) 0.315
Male gender 1020 (50%) 154 (49.2%) 184 (52.6%) 186 (51.5%) 168 (49.3%) 164 (50.3%) 164 (47.3%) 0.976
Diagnosis Brain trauma 255 (12.5%) 43 (13.7%) 54 (15.4%) 51 (14.1%) 41 (12.0%) 28 (8.6%) 38 (11.0%) 0.192
Brain tumor 1271 (62.4%) 185 (59.1%) 221 (63.1%) 240 (66.5%) 200 (58.7%) 209 (64.1%) 216 (62.2%) 0.911
Congenital disorders 23 (1.1%) 4 (1.3%) 5 (1.4%) 3 (0.8%) 7 (2.1%) 2 (0.6%) 2 (0.6%) 0.436
Vascular brain diseases 454 (22.3%) 77 (24.6%) 60 (17.1%) 63 (17.5%) 89 (26.1%) 80 (24.5%) 85 (24.5%) 0.066
Other diseases 29 (1.4%) 3 (1.0%) 10 (2.9%) 4 (1.1%) 4 (1.2%) 4 (1.2%) 4 (1.2%) 0.302
Surgeries Craniotomy 1537 (75.4%) 230 (73.5%) 261 (74.6%) 279 (77.3%) 262 (76.8%) 245 (75.2%) 260 (74.9%) 0.998
INSD 650 (31.9%) 101 (32.3%) 130 (37.1%) 124 (34.3%) 112 (32.8%) 94 (28.8%) 89 (25.6%) 0.227
Endovascular surgery 194 (9.5%) 31 (9.9%) 37 (10.6%) 26 (7.2%) 40 (11.7%) 25 (7.7%) 35 (10.1%) 0.407
EETS 87 (4.3%) 13 (4.2%) 15 (4.3%) 15 (4.2%) 14 (4.1%) 15 (4.6%) 15 (4.3%) 1.000
Spinal surgery 4 (0.2%) 1 (0.3%) 0 (0.0%) 0 (0.0%) 0 (0.0%) 2 (0.6%) 1 (0.3%) 0.377
Other surgeries 873 (42.8%) 151 (48.2%) 161 (46.0%) 156 (43.2%) 146 (42.8%) 127 (39.0%) 132 (38.0%) 0.523
Outcomes Recovery 80 (3.9%) 15 (4.8%) 14 (4.0%) 14 (3.9%) 19 (5.6%) 9 (2.8%) 9 (2.6%) 0.365
Positive dynamics 934 (45.8%) 133 (42.5%) 153 (43.7%) 170 (47.1%) 159 (46.6%) 150 (46.0%) 169 (48.7%) 0.934
No dynamics 210 (10.3%) 34 (10.9%) 41 (11.7%) 37 (10.2%) 30 (8.8%) 29 (8.9%) 39 (11.2%) 0.818
Negative dynamics 505 (24.8%) 81 (25.9%) 67 (19.1%) 78 (21.6%) 92 (27.0%) 96 (29.4%) 91 (26.2%) 0.153
Death 307 (15%) 50 (16.0%) 75 (21.4%) 62 (17.2%) 41 (12.0%) 41 (12.6%) 38 (11.0%) 0.009
   Median [Q1;Q3] Median [Q1;Q3] Median [Q1;Q3] Median [Q1;Q3] Median [Q1;Q3] Median [Q1;Q3] Median [Q1;Q3] p-value
  Age, years 46 [26.0; 59.0] 44 [25.0; 57.0] 44 [25.0; 58.0] 47 [26.0; 60.0] 44 [25.0; 57.0] 50 [30.0; 59.75] 48 [24.5; 60.5] 0.099
CCI score 3 [2.0; 5.0] 3 [2.0; 4.0] 3 [2.0; 5.0] 3 [2.0; 5.0] 3 [2.0; 4.0] 3 [2.0; 5.0] 3 [2.0; 4.0] 1.000
Length of stay in ICU, days 10 [6.0; 22.0] 13 [7.0; 27.0] 12 [6.0; 25.0] 10 [6.0; 24.0] 8 [6.0; 22.0] 9 [6.0; 22.0] 8 [5.0; 17.0] 0.010
  1. Abbreviations: INSD Implantation of neurosurgical devices, EETS Endoscopic endonasal transsphenoidal surgery, CCI Charlson comorbidity index
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