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Table 3 Univariable logistic regression analysis of definite nosocomial SARS-CoV-2 cases with matched controls (n = 76) and their respective controls (n = 76) for the outcome nosocomial SARS-CoV-2 acquisition

From: Risk factors for nosocomial SARS-CoV-2 infections in patients: results from a retrospective matched case–control study in a tertiary care university center

Parameter

Characteristic

Odds ratio (CI95)

p value

Age

per year

1.01 (0.99–1.04)

0.301

Sex (male vs. female)

male

1 (0.52–1.92)

1.00

Charlson Comorbidity Index

per score point

1.03 (0.93–1.14)

0.573

Admission via ER (yes vs. no)

yes

1 (0.45–2.23)

1.00

ICU-stay during the relevant timeframe (yes vs. no)

yes

0.73 (0.29–1.81)

0.493

Number of documented procedure codes in the patient files during the relevant timeframe

per additional procedure code

0.94 (0.9–0.99)

0.017

Number of ward transfers during the relevant timeframe

per additional ward transfer

1.02 (0.76–1.38)

0.880

Number of patient room transfers during the relevant timeframe

per additional room transfer

0.93 (0.76–1.14)

0.509

Number of contact patients during relevant timeframe

per additional contact patient

0.97 (0.88–1.06)

0.439

Number of contact patient-days during relevant timeframe

per additional contact patient-day

0.99 (0.97–1.01)

0.147

Present at a ward with a SARS-CoV-2 outbreak reported to authorities during the stay or up to 14 days later (yes vs. no)

yes

14.5 (3.46–60.77)

 < 0.001

Documented contact to a (suspected) SARS-CoV-2 case during the relevant timeframe (yes vs. no)

yes

21.5 (5.21–88.75)

 < 0.001

Documented contact to a (suspected) SARS-CoV-2 case during the relevant timeframe before hospital admission (yes vs. no)

yes

n.d

 

Documented contact to a (suspected) SARS-CoV-2 case during the relevant timeframe after hospital admission (yes vs. no)

yes

21.5 (5.21–88.75)

 < 0.001

Documented contact to (suspected) SARS-CoV-2 positive patients during the relevant timeframe* (yes vs. no)

yes

28 (3.81–205.79)

0.001

Documented contact to (suspected) SARS-CoV-2 positive staff during the relevant timeframe* (yes vs. no)

yes

16 (2.12–120.65)

0.007

  1. Nosocomial SARS-CoV-2 cases, where the first positive SARS-CoV-2 test was from a sample taken more than 10 days after hospital admission, were considered definite nosocomial cases. For SARS-CoV-2 cases, the relevant timeframe was defined as the 14 days preceding the first positive test. For controls, the relevant timeframe comprised of 14 days. Age represents the age in years at the beginning of the relevant timeframe. Contact patients were defined as patients placed in the same patient room for any period of time. Contact patient-days are the product of contact patients and the duration of contact in days. Abbreviations: CI95 – 95% confidence interval; ER – emergency room; ICU – intensive care unit; IQR – interquartile range. *Contact to more than one group of SARS-CoV-2 positive persons (e.g. patients and staff) was possible. In that case, both were recorded and counted
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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