Skip to main content

Table 1 Baseline information on patients (n = 326) included in the study on sex, age at admission, length of stay at the neonatal intensive care unit (NICU), treatment outcome and diagnoses

From: Clonal spread of carbapenem-resistant Klebsiella pneumoniae among patients at admission and discharge at a Vietnamese neonatal intensive care unit

  Patients with admission samples (n = 326) Patients with both admission and discharge samples (n = 248)
Total Admission +  Admission − p Total Discharge +  Discharge − p Admission + Discharge − Admission − Discharge +  p Admission − Discharge − p Admission + Discharge +  p
Number of patients 326 69 257 248 184 64 5 137   59   47
Sex
Female 118 (37%) 28 (8.5%) 90 (28%) 0.39 91 (37%) 73 (30%) 18 (7%) 0.13 0 49 (20%) 0.59 18 (7%) 0.22 24 (10%) 0.042
Male 202 (63%) 39 (12%) 163 (50%)   153 (63%) 108 (44%) 45 (18%)   5 (2%) 86 (35%)   40 (16%)   22 (9%)  
Missing data 6 (2%) 2 (0.6%) 4 (1%) 4 (2%) 3 (1%) 1 (0.4%) 0 2 (1%) 1 (0.4%) 1 (0.4%)
Age at admission
Median (days) 4 16 3  < 0.001 4 6 3 0.03 5 3 3 16  < 0.001
Missing data 13 (4%) 2 (0.6%) 11 (3%) 8 (3%) 7 (3%) 1 (0.4%) 0 7 (3%) 1 (0.4%) 0
Stay at NICU
Median (days) 5 6 5 0.26 5 7 3  < 0.001 5 7 3 9  < 0.001
Missing data 19 (6%) 4 (1%) 15 (5%) 10 (4%) 8 (3%) 2 (1%) 1 (0.4%) 7 (3%) 1 (0.4%) 1 (0.4%)
Treatment outcome
Deceased 57 (18%) 19 (6%) 38 (12%) 0.012 42 (17%) 35 (14%) 7 (3%) 0.118 1 (0.4%) 22 (9%) 0.69 6 (2%) 0.097 13 (5%) 0.023
Withdrawn 24 (8%) 10 (3%) 14 (4%) 0.1 21 (9%) 17 (7%) 4 (2%) 0.43 0 8 (3%) 0.1 4 (2%) 0.56 9 (4%) 0.003
Discharged 34 (11%) 9 (3%) 25 (8%) 0.41 30 (12%) 27 (11%) 3 (1%) 0.3 0 19 (8%) 0.34 3 (2%) 0.051 8 (3%) 0.22
Transferred 204 (64%) 29 (9%) 175 (54%)  < 0.001 150 (62%) 100 (40%) 50 (20%) 0.002 4 (2%) 85 (34%) 0.54 46 (19%) 0.003 15 (6%)  < 0.001
Missing data 7 (2%) 2 (0.6%) 5 (2%) 5 (2%) 5 (2%) 1 (0.4%) 0 3 (1%) 0 2 (1%)
Diagnosis
RSD 203 (65%) 43 (13%) 160 (49%) 0.58 158 (66%) 125 (50%) 33 (13%) 0.018 4 (2%) 95 (38%) 0.076 29 (12%) 0.008 30 (12%) 0.69
Pre-term 82 (26%) 17 (5%) 65 (20%) 0.9 70 (29%) 51 (21%) 19 (8%) 0.75 1 (0.4%) 39 (16%) 0.95 17 (7%) 0.88 12 (5%) 0.77
Pneumonia 71 (23%) 21 (6%) 50 (15%) 0.026 58 (24%) 48 (19%) 10 (4%) 0.09 0 31 (13%) 0.65 10 (4%) 0.19 17 (7%) 0.012
Sepsis 41 (13%) 8 (2%) 33 (10%) 0.9 38 (16%) 31 (13%) 7 (3%) 0.26 1 (0.4%) 24 (10%) 0.33 6 (2%) 0.21 7 (3%) 0.98
CHD 26 (8%) 13 (4%) 13 (4%)  < 0.001 16 (7%) 13 (5%) 3 (1%) 0.51 1 (0.4%) 5 (2%) 0.039 2 (1%) 0.28 8 (3%)  < 0.001
Hyperbilirubinemia 26 (8%) 1 (0.3%) 25 (8%) 0.03 21 (9%) 15 (6%) 6 (2%) 0.76 1 (0.4%) 15 (6%) 0.14 5 (2%) 0.99 0 0.023
PDA 11 (4%) 4 (1%) 7 (2%) 0.18 7 (3%) 5 (2%) 2 (1%) 0.86 0 2 (1%) 0.14 2 (1%) 0.76 3 (1%) 0.087
Gastroenteritis 8 (3%) 1 (0.3%) 7 (2%) 0.58 6 (2%) 4 (2%) 2 (1%) 0.67 0 3 (1%) 0.76 2 (1%) 0.57 1 (0.4%) 0.92
Pulmonary hypertension 7 (2%) 0 7 (2%) 0.18 4 (2%) 1 (0.4%) 3 (1%) 0.023 0 1 (0.4%) 0.21 3 (1%) 0.015 0 0.34
Asphyxia 6 (2%) 1 (0.3%) 5 (2%) 0.83 5 (2%) 4 (2%) 1 (0.4%) 0.77 0 3 (1%) 0.86 1 (0.4%) 0.85 1 (0.4%) 0.92
Pleural effusion 5 (2%) 0 5 (2%) 0.26 5 (2%) 4 (2%) 1 (0.4%) 0.77 0 4 (2%) 0.28 1 (0.4%) 0.85 0 0.29
Other 71 (23%) 18 (6%) 53 (16%) 49 (20%) 34 (14%) 15 (6%) 1 (0.4%) 23 (9%) 14 (6%) 11 (4%)
Missing data 15 (5%) 6 (2%) 9 (3%) 7 (3%) 5 (2%) 2 (1%) 0 2 (1%) 2 (1%) 3 (1%)
  1. Since discharge samples were not collected from all patients, patients with admission samples (i.e., all included samples) were analysed as a set in terms of all included patients and characteristics of admission-positive and admission-negative patients, whereas analyses in terms of discharge-positive and discharge-negative were analysed on a smaller set of patients including all patients from whom discharge samples were taken (n = 248). Due to the large number of comparisons, associations were considered significant for p < 0.01 (marked in bold). Due to the low number of patients which were positive at admission but negative at discharge (n = 5), this cohort was excluded from the statistical analysis
  2. RSD, Respiratory distress syndrome; CHD, Congenital heart disease; PDA, Persistent ductus arteriosus