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Table 4 Profiling of genetic mutations and MICs for LZD-resistant MTB isolates

From: Prevalence of extensively drug-resistant tuberculosis in a Chinese multidrug-resistant TB cohort after redefinition

Locus Mutation No. of isolates with corresponding MIC (μg/ml) Total (%)
2 4 8  > 8
rplC Cys154Arg   5 5 2 12 (40.0)
23S rRNA G2270C   1    1 (3.3)
  G2270T   2 1   3 (10.0)
Wild-type 7 6 1   14 (46.7)
Total 7 14 7 2 30 (100.0)
  1. MIC, minimum inhibitory concentration; LZD, linezolid; MTB, Mycobacterium tuberculosis