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Table 3 Profiling of genetic mutations and MICs for BDQ-resistant MTB isolates

From: Prevalence of extensively drug-resistant tuberculosis in a Chinese multidrug-resistant TB cohort after redefinition

Locus Mutation No. of isolates with corresponding MIC (μg/ml) Total (%)
0.25 0.5 1
Rv0678 Ala86Val   1   1 (10.0)
  Ile108Thr   1   1 (10.0)
  Arg109Pro 1    1 (10.0)
  Deletion A in codon 110   1   1 (10.0)
Wild-type 4 1 1 6 (60.0)
Total 5 4 1 10 (100.0)
  1. MIC, minimum inhibitory concentration; BDQ, bedaquiline; MTB, Mycobacterium tuberculosis