Methods | Extended gold standarda | Sensitivity (95% confidence interval) | Specificity (95% confidence interval) | |
---|---|---|---|---|
Positive (n = 41) | Negative (n = 39) | |||
Quantitative culture | ||||
Positive | 40 | 1 | 97.6% (87.1–99.9) | 97.4% (86.5–99.9) |
Negative | 1 | 38 | ||
Enrichment culture (4 samples could not be tested) | ||||
Positive | 34 | 0 | 89.5% (75.2–97.1) | 100% (90.8–100) |
Negative | 4 | 38 | ||
In-house qPCR (1 sample could not be tested) | ||||
Positive | 38 | 11 | 92.7% (80.1–98.5) | 71.1% (54.1–84.6) |
Negative | 3 | 27 | ||
GeneXpert PA assay | ||||
Positive | 40 | 0 | 97.6% (87.1–99.9) | 100% (91.0–100) |
Negative | 1 | 39 | ||
Semi-quantitative culture | ||||
Positive | 40 | 0 | 97.6% (87.1–99.9) | 100% (91.0–100) |
Negative | 1 | 39 |