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Table 4 Presence of carbapenemase* and Mrc1 genes in isolates by organism, Thailand, 2016–2018

From: Molecular epidemiology of carbapenem-resistant Enterobacterales in Thailand, 2016–2018

 

n (% of isolates by organism)

P value

Carbapenemase Gene

Total

(N = 3946)

Organisms

Klebsiella pneumoniae

(N = 2659)

Escherichia coli

(N = 799)

Enterobacter cloacae

(N = 113)

Citrobacter freundii

(N = 12)

Other

(N = 102)

NDM

2501 (63)

1577 (55)

776 (94)

736 (59)

11 (100)

64 (65)

 < .0001

OX-48-like

1892 (48)

1703 (59)

149 (18)

27 (22)

1 (9)

12 (12)

 < .0001

IMP

97 (2)

46 (2)

1 (< 1)

31 (25)

0 (0)

19 (19)

 < .0001

No CP Gene

102 (3)

74 (3)

9 (1)

18 (16)

0 (0)

1 (1)

 < .0001

Mcr1

10 (< 1)

5 (< 1)

5 (1)

0 (0)

0 (0)

0 (0)

0.23

  1. *Not mutually exclusive: 634 had NDM and OXA and 7 had IMP and OXA, 5 had NDM and IMP, 6 Mcr1 and NDM, 3 Mcr1 and OXA-48-like
  2. *No VIM or KPC
  3. p-value using chi-square or fisher exact test to compare presence of carbapenemase genes and MCR-1 across organisms