Outcome | Outcome measurement instrument | Objective/Subjective | Overall quality of evidence |
---|---|---|---|
The total number of antimicrobial courses prescribed | (1) Number of antimicrobial courses started per 1000 resident-days [16,17,18] | Objective |  +  |
(2) Number of antibiotic transactions per 1000 resident-days [19] | Objective | ? | |
(3) Point prevalence of antimicrobial use [20] | Objective | ? | |
(4) Total number of antimicrobial courses [21] | Objective | ? | |
(5) Mean number of residents treated with antimicrobial per month [22] | Objective | ? | |
Appropriateness of antimicrobial prescribing | (6) Loeb minimum criteria for initiating antibiotic therapy in SSTIs, RTIs, UTIs, fever where the focus of infection is unknown [23] | Subjective | ? |
(7) Revisited McGeer criteria for diagnosing infection: SSTIs, RTIs, UTIs, gastrointestinal tract infections, systemic infections [24, 25] | Subjective | - | |
(8) Crnich algorithm for the initiation of antibiotics for UTIs [26] | Subjective | - | |
(9) Van Buul algorithms to evaluate appropriateness of initiating or withholding antibiotics in SSTIs, RTIs, UTIs [27] | Subjective | ? | |
Subjective | - | ||
Days of therapy per 1000 resident-days | (11) Rate of antimicrobial days of therapy per 1000 resident-days [16,17,18] | Objective |  +  |
Objective | ? | ||
Rate of antimicrobial resistance | (13) Number of cases with specific (non-) resistant organisms [30] | Subjective | - |
(14) Number of specific (non-) resistant isolates/ organisms [31, 32] | Subjective | - | |
(15) Drug Resistance Index [33] | Subjective | - | |
Mortality related to infection | (16) Rate of mortality related to infection per 1000 resident-days [34] | Subjective | - |
(17) Proportion of mortality related to infection [30] | Subjective | - |