Table 2 Resistance genes that contribute to spatial patterns within the sub-population where metagenomic analysis was performed
Gene | SS (trace) | Pseudo-F | p value | Explained variance (proportion) | Resistance mechanism |
|---|---|---|---|---|---|
OXA-1 | 66.812 | 9.953 | 0.001 | 0.322 | Beta-lactams resistance |
mcr-1.9 | 56.881 | 7.916 | 0.004 | 0.274 | Peptide antibiotic resistance |
BRP(MBL) | 55.229 | 7.603 | 0.005 | 0.266 | Beta-lactams resistance |
dfrA14 | 48.845 | 6.454 | 0.006 | 0.235 | Diaminopyrimidine resistance |
omp38 | 45.105 | 5.823 | 0.011 | 0.217 | Beta-lactams resistance |
rmtB | 42.099 | 5.336 | 0.012 | 0.203 | Aminoglycosides resistance |
NDM-7 | 40.965 | 5.157 | 0.016 | 0.197 | Beta-lactams resistance |
catB3 | 40.085 | 5.020 | 0.014 | 0.193 | Phenicol resistance |
vanSG | 37.290 | 4.593 | 0.024 | 0.180 | Glycopeptide resistance |
tsnR | 36.330 | 4.450 | 0.017 | 0.175 | Peptide antibiotic resistance |
mgtA | 36.330 | 4.450 | 0.015 | 0.175 | Macrolide resistance |
mdfA | 36.019 | 4.404 | 0.023 | 0.173 | Multidrug efflux pump |
kpnF | 32.752 | 3.930 | 0.037 | 0.158 | Multidrug efflux pump |
vanN | 32.473 | 3.890 | 0.041 | 0.156 | Glycopeptide resistance |
vanO | 31.383 | 3.736 | 0.048 | 0.151 | Glycopeptide resistance |
CRP | 31.383 | 3.736 | 0.049 | 0.151 | Multidrug efflux pump |
vgaE | 31.383 | 3.736 | 0.048 | 0.151 | Streptogramin resistance |
fusB | 31.309 | 3.726 | 0.039 | 0.151 | Fusidic acid resistance |
cfxA6 | 30.898 | 3.668 | 0.046 | 0.149 | Beta-lactams resistance |