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Table 3 Antimicrobial resistance rates of K. pneumoniae strains

From: Clinical and microbiological characteristics of nosocomial, healthcare-associated, and community-acquired Klebsiella pneumoniae infections in Guangzhou, China

Antimicrobials Nosocomial HCA CA P-value
(n = 98) (n = 195) (n = 86) HCA versus Nosocomial CA versus Nosocomial CA versus HCA
Ampicillin 96 (98.0%) 195 (100.0%) 82 (95.4%) 0.111 0.420 0.002
Cefazolin 68 (69.4%) 131 (67.2%) 36 (41.9%) 0.702 0.000 0.000
Cefuroxime 58 (59.2%) 114 (58.5%) 27 (31.4%) 0.906 0.000 0.000
Ceftriaxone 56 (57.1%) 109 (55.9%) 26 (30.2%) 0.839 0.000 0.000
Ceftazidime 43 (43.9%) 85 (43.6%) 18 (20.9%) 0.963 0.001 0.000
Cefepime 41 (41.8%) 87 (44.6%) 15 (17.4%) 0.651 0.000 0.000
Imipenem 20 (20.4%) 57 (29.2%) 4 (4.7%) 0.105 0.002 0.000
Meropenem 21 (21.4%) 57 (29.2%) 4 (4.7%) 0.154 0.001 0.000
Ertapenem 24 (24.5%) 58 (29.7%) 4 (4.7%) 0.345 0.000 0.000
Amoxicillin/Clavulanic Acid 44 (44.9%) 78 (40.0%) 13 (15.1%) 0.422 0.000 0.000
Cefoperazone/Sulbactam 41 (41.8%) 66 (33.9%) 9 (10.5%) 0.180 0.000 0.000
Piperacillin/ Tazobactam 43 (43.9%) 74 (38.0%) 8 (9.3%) 0.328 0.000 0.000
Aztreonam 47 (48.0%) 102 (52.3%) 22 (25.6%) 0.482 0.002 0.000
Cefoxitin 31 (31.6%) 73 (37.4%) 11 (12.8%) 0.327 0.002 0.000
Ciprofloxacin 45 (45.9%) 103 (52.8%) 21 (24.4%) 0.265 0.002 0.000
Levofloxacin 31 (31.6%) 90 (46.2%) 14 (16.3%) 0.017 0.016 0.000
Amikacin 36 (36.7%) 46 (23.6%) 6 (7.0%) 0.018 0.000 0.001
Gentamicin 47 (48.0%) 91 (46.6%) 24 (27.9%) 0.834 0.005 0.004
Trimethoprim/Sulfamethoxazole 52 (53.1%) 106 (54.4%) 34 (39.5%) 0.833 0.067 0.028
Tigecycline 1 (1.0%) 4 (2.1%) 1 (1.2%) 0.667 1.000 1.000
ESBL-production 40 (40.8%) 70 (35.9%) 21 (24.4%) 0.412 0.018 0.072
Multidrug resistance 52 (53.1%) 102 (52.3%) 20 (23.3%) 0.903 0.000 0.000
  1. Data are presented as number (%)
  2. Bold values suggest statistical significance