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Table 2 Values for the quality indicators at baseline and across the post-intervention period for both groups

From: Impact of a multifaceted intervention to improve antibiotic prescribing: a pragmatic cluster-randomised controlled trial

ESAC Quality

Indicators [25]

Group

Period

Baseline (median 48 monthsb)

Post-intervention (median 19 monthsb)

1. DID of antibiotics for systemic use

Intervention

15.9 (15.8–16.0)

13.8 (13.7–14.0)

Control

14.9 (14.8–15.0)

13.5 (13.4–13.6)

2. DID of penicillins

Intervention

9.1 (9.1–9.2)

7.9 (7.8–8.0)

Control

8.0 (7.9–8.0)

7.3 (7.3–7.4)

3. DID of cephalosporins

Intervention

1.9 (1.9–1.9)

1.5 (1.5–1.5)

Control

1.8 (1.8–1.8)

1.5 (1.5–1.5)

4. DID of macrolides, lincosamides and streptogramins

Intervention

1.6 (1.6–1.6)

1.4 (1.4–1.4)

Control

1.7 (1.7–1.8)

1.6 (1.5–1.6)

5. DID of quinolones

Intervention

2.1 (2.1–2.1)

1.9 (1.8–1.9)

Control

2.1 (2.1–2.1)

1.9 (1.9–2.0)

6. PCT of beta-lactamase sensitive penicillinsa

Intervention

0.6 (0.6–0.7)

0.6 (0.5–0.6)

Control

0.4 (0.4–0.4)

0.4 (0.3–0.4)

7. PCT of combinations of penicillins with beta-lactamase inhibitors a

Intervention

42.1 (42.0–42.3)

40.0 (39.8–40.3)

Control

39.0 (38.9–39.2)

38.2 (38.0–38.4)

8. PCT of 3rd- and 4th-generation cephalosporins a

Intervention

4.0 (3.9–4.0)

2.8 (2.7–2.9)

Control

4.2 (4.8–4.3)

3.3 (3.2–3.4)

9. PCT of quinolones

Intervention

13.3 (13.2–13.4)

13.4 (13.2–13.5)

Control

14.3 (14.2–14.4)

14.3 (14.1–14.4)

10. Ratio of consumption of broad- to narrow-spectrum penicillins, cephalosporins and macrolides

Intervention

68.9 (67.6–70.1)

49.3 (47.5–51.0)

Control

59.9 (58.8–60.9)

45.0 (43.6–46.5)

  1. Abbreviations. PCT Percentage, DID Defined daily doses per 1000 inhabitants per day, ESAC European Surveillance of Antimicrobial Consumption
  2. a Percentage of total consumption of antibiotics for systemic use in DID
  3. b The interventions were implemented from December 2011 to July 2012