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Table 4 Distributions of fosfomycin-resistant related genes corresponding MIC values among MRSA isolates

From: Prevalence of fosfomycin resistance and gene mutations in clinical isolates of methicillin-resistant Staphylococcus aureus

uhpT mutationa

glpT mutationb

murA mutationc

fosB gene

t002

t037

Other spa types

Total

n

FOS range

n

FOS range

n

FOS range

n

FOS range

Wild type

Wild type

Wild type

Positive

0

–

0

–

1

128

1

128

Wild type

Type I

Wild type

Positive

1

>  2048

0

–

0

–

1

>  2048

Wild type

Type I

Wild type

Negative

3

>  2048

0

–

1

>  2048

4

>  2048

Wild type

Type II

Type I

Negative

0

–

2

>  2048

0

–

2

>  2048

Wild type

Type VI

Wild type

Negative

0

–

1

64

0

–

1

64

Type I

Wild type

Type I

Negative

0

–

1

128

0

–

1

128

Type I

Type I

Wild type

Positive

9

>  2048

0

–

0

–

9

>  2048

Type I

Type I

Wild type

Negative

31

1024 - >  2048

0

–

7

>  2048

38

1024 - >  2048

Type I

Type I

Type III

Positive

1

>  2048

0

–

0

–

1

>  2048

Type I

Type I

Type IV

Negative

2

>  2048

0

–

0

–

2

>  2048

Type I

Type I

Type V

Negative

1

>  2048

0

–

0

–

1

>  2048

Type I

Type I

Type VII

Negative

1

>  2048

0

–

0

–

1

>  2048

Type I

Type III

Wild type

Negative

1

128

0

–

0

–

1

128

Type I

Type IV

Wild type

Negative

1

>  2048

0

–

0

–

1

>  2048

Type II

Type I

Wild type

Negative

1

>  2048

0

–

0

–

1

>  2048

Type II

Type I

Type VI

Negative

0

–

0

–

1

>  2048

1

>  2048

Type III

Type I

Type II

Negative

0

–

0

–

1

256

1

256

Type IV

Type V

Type I

Negative

0

–

1

2048

0

–

1

2048

  1. a Type I: A279V; Type II: A297V/E225D; Type III: F267L/L281X; Type IV: G161R; Wild type: no mutations detected
  2. b Type I: A434V; Type II: W147X; Type III: F197I; Type IV: A434V/G399S; Type V: C57X; Type VI: T313K; Wild type: no mutations detected
  3. c Type I: G257D; Type II: D278E; Type III: deletion at position 717; Type IV: G322S; Type V: L162I; Type VI: E271Q; Type VII: G240R; Wild type: no mutations detected