Method | MLVA | MLST | PFGE | cgMLST | WGS | Transposon analysis |
---|---|---|---|---|---|---|
Principle | Fragment length of variable tandem repeat loci | Sequences of multiple house keeping genes | DNA based macro restriction analysis | Genome-wide gene-by-gene approach of 1423 genes on allelic level | Whole genome analysis | Sequences of transposon content and integration |
Reproducibility | High | High | Medium | Excellent | Excellent | Excellent |
Ease of performance | Very easy | Easy | Laborious | Easy | Easy | Easy |
Data interpretation | Easy-moderate | Easy | Difficult | Easy | Various | Moderate |
Ease of data exchange | Easy | Easy | Difficult | Easy | Possible | Possible |
Costs | Low | Medium | Medium | High, extracted from WGS | High | High, extracted from WGS |
Discriminatory power | Low | Medium | High | Excellent | Excellent | Additional |