Table 2 Analysis of factors associated with carbapenem-non-susceptibility in invasive Acinetobacter spp. isolates
| Â | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
OR | (95% CI) | p-value | OR | (95% CI) | p-value | |
Year of sampling | ||||||
 2013–2017 | 1.02 | (0.88–1.18) | 0.844 | 1.03 | (0.94–1.13) | 0.571 |
European region | ||||||
 Northern | 1 | – | – | 1 | – | – |
 Western | 2.37 | (0.98–5.74) | 0.056 | 2.66 | (1.04–6.82) | 0.041 |
 Southern | 109 | (47.2–250) | < 0.001 | 83.76 | (33.79–207.66) | < 0.001 |
 Eastern | 88.4 | (38.3–204) | < 0.001 | 75.87 | (31.23–184.32) | < 0.001 |
Patient gender | ||||||
 Female | 1 | – | – | 1 | – | – |
 Male | 1.54 | (1.36–1.73) | < 0.001 | 1.17 | (1.03–1.33) | 0.013 |
Patient age | ||||||
 < 1 years | 0.36 | (0.16–0.82) | 0.014 | 0.24 | (0.10–0.59) | 0.002 |
 1–19 years | 0.20 | (0.12–0.32) | < 0.001 | 0.28 | (0.16–0.49) | < 0.001 |
 20–39 years | 1 | – | – | 1 | – | – |
 40–59 years | 1.36 | (1.01–1.84) | 0.044 | 1.25 | (0.88–1.77) | 0.217 |
 60–79 years | 1.20 | (0.91–1.58) | 0.195 | 1.21 | (0.92–1.56) | 0.178 |
 80+ years | 0.78 | (0.58–1.07) | 0.123 | 1.16 | (0.85–1.59) | 0.352 |
Specimen (sampling site) | ||||||
 Blood | 1 | – | – | 1 | – | – |
 CSF | 1.42 | (1.00–2.01) | 0.052 | 0.78 | (0.45–1.35) | 0.373 |
Hospital unit type | ||||||
 Internal medicine | 1 | – | – | 1 | – | – |
 Intensive care | 6.62 | (5.26–8.33) | < 0.001 | 3.79 | (2.94–4.88) | < 0.001 |
 Oncology | 0.49 | (0.32–0.74) | < 0.001 | 0.61 | (0.43–0.87) | 0.006 |
 Surgery | 1.47 | (1.16–1.88) | 0.002 | 1.17 | (0.85–1.60) | 0.341 |
 Other | 0.64 | (0.47–0.85) | 0.003 | 0.81 | (0.62–1.06) | 0.13 |
Season | ||||||
 Warm months | 0.83 | (0.73–0.94) | 0.003 | 0.86 | (0.73–1.02) | 0.087 |
 Cold months | 1 | – | – | 1 | – | – |