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Table 3 Antimicrobial resistance rates of clinical K. pneumoniae strains

From: Clinical characteristics of patients with pneumonia caused by Klebsiella pneumoniae in Taiwan and prevalence of antimicrobial-resistant and hypervirulent strains: a retrospective study

Variable

CAP (n = 68)

HCAP (n = 74)

HAP (n = 134)

p value

CAP vs. HCAP

HCAP vs. HAP

CAP vs. HAP

Amikacin

0 (0.0)

0 (0.0)

6 (4.5)

N/A

0.091

0.099

Gentamicin

3 (4.4)

13 (17.6)

22 (16.4)

0.016

0.832

0.013

Cefuroxime

7 (10.3)

27 (36.5)

64 (47.8)

< 0.001

0.117

< 0.001

3rd generation cephalosporina

5 (7.4)

19 (25.7)

57 (42.5)

0.004

0.016

< 0.001

Ciprofloxacin

3 (4.4)

22 (29.7)

52 (38.8)

< 0.001

0.191

< 0.001

Levofloxacin

3 (4.4)

22 (29.7)

51 (38.1)

< 0.001

0.228

< 0.001

Ertapenem

2 (2.9)

11 (14.9)

33 (24.6)

0.018

0.099

< 0.001

Imipenem

0 (0.0)

0 (0.0)

7 (5.2)

N/A

0.052

0.098

Tigecycline

2 (2.9)

1 (1.4)

10 (7.5)

0.607

0.101

0.344

Wild-type antibiotic susceptibilityb

60 (88.2)

40 (54.1)

58 (43.3)

< 0.001

0.149

< 0.001

Multidrug resistancec

7 (10.3)

27 (36.5)

66 (49.3)

< 0.001

0.076

< 0.001

  1. Data are presented as number (%) of isolates resistant to the antibiotic indicated, unless stated otherwise
  2. N/A not applicable
  3. aIncluding either ceftriaxone and ceftazidime
  4. bWild-type antibiotic susceptibility was defined in the isolates as susceptibility to all antibiotics except for ampicillin
  5. cMultidrug resistance was defined in the isolates as nonsusceptibility to at least one agent in three or more antimicrobial categories