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Table 3 Incremental cost-effectiveness ratios for VRE screening and isolation program in various scenarios

From: Vancomycin-resistant enterococci (VRE) screening and isolation in the general medicine ward: a cost-effectiveness analysis

Scenario

Incremental Cost

Incremental QALYs

ICER ($/QALY)

Probability of CE (at $7500/QALY)

Probability of CE (at $50,000/QALY)

VRE Prevalence in-hospital, 10x (outbreak)

122.79

0.0525

2340

0.545

0.556a

Room costs excluded ($0)

20.58

0.0077

2682

0.506

0.508a

Number of beds in ward [33]

109.78

0.0093

11,812

0.505

0.518a

Program length (5000 admissions)

113.05

0.0023

50,094

0.457

0.499a

Isolation, decreased effectiveness (0.75)

99.52

0.0002

510,676

0.458

0.476a

Time horizon, 1 year

109.61

0.0001

856,297

0

0.259

Universal screening VRE screening and isolation

151.44

−0.0039

Dominated

0.484

0.500a

VRE Prevalence in-hospital, 0.5x

108.41

−0.0112

Dominated

0.479

0.501a

  1. aSignifies asymptote at that probability at $50,000/QALY
  2. CE cost-effectiveness, ICER incremental cost-effectiveness ratio, QALY quality-adjusted life year, VRE vancomycin-resistant enterococci