Table 7 Studies describing hospital costs among patients with resistant and multi-drug resistant A. baumannii
From: Economic burden of antibiotic resistance in ESKAPE organisms: a systematic review
Author | Bacteria | Comparison | Description of cost | Median cost in 2015 USD | Mean cost in 2015 USD | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Median cost | Case | Control | Increase | Ratio | P-value | Mean cost | Case | Control | Increase | Ratio | P-value | |||
Cui et al. [98] | A. baumannii | IRAB | ISAB | Total hospital cost | Median (IQR) | 16,835(7619–46,479) | 7783(3583–36,235) | 9052(4035–10,244) | 2.16 | < 0.01 |  |  |  |  |  |  |
A. baumannii | IRAB | ISAB | Antibiotic cost | Median (IQR) | 2558(793–5799) | 1257(519–3835) | 1301(274–1964) | 2.03 | < 0.01 |  |  |  |  |  |  | |
Zhen et al. [99] | A. baumannii | CRAB | CSAB | Total hospital cost |  |  |  |  |  |  | Mean (SD) | 30,575(17) | 17(11) | 10,792(7) | 1.55 | < 0.000 |
A. baumannii | CRAB | CSAB | Antibiotic cost |  |  |  |  |  |  | Mean (SD) | 3047(19) | 19(11) | 1355(8) | 1.80 | < 0.000 | |
Lemos et al. [108] | A. baumannii | CRAB | CSAB | Total hospital cost |  |  |  |  |  |  | Mean (95%CI) | 11,969(10593–13,154) | 10,593(6540–8452) | 4541(2970–5948) | 1.61 | < 0.001 |
A. baumannii | CRAB | CSAB | Antibiotic cost |  |  |  |  |  |  | Mean (95%CI) | 3854(3234–4383) | 3234(2117–3238) | 1198(407–1996) | 1.45 | 0.0020 | |
A. baumannii | CRAB | CSAB | Total hospital cost |  |  |  |  |  |  | Mean (SD) | 12,457(7728) | 7728(4150) | 4894(3579) | 1.65 | < 0.001 | |
A. baumannii | CRAB | CSAB | Antibiotic cost | Â | Â | Â | Â | Â | Â | Mean (SD) | 4316(4242) | 4242(2152) | 1708(2091) | 1.65 | 0.0020 | |
Lautenbach et al. [100] | A. baumannii | IRAB | ISAB | Hospital charge after culture |  |  |  |  |  | Mean (95% CI) | 393,086(276636–509,536) | 276,636(252785–396,002) | 68,692(23851–113,533) | 1.21 | 0.0300 | |
Lee et al. [101] | A. baumannii | MDR | Non-MDR | Total hospital cost | Â | Â | Â | Â | Â | Â | Mean | 15,881 | 7739 | 8141 | 2.05 | 0.0460 |
A. baumannii | MDR | Non-MDR | ICU cost | Â | Â | Â | Â | Â | Â | Mean | 13,933 | 4311 | 9622 | 3.23 | 0.0020 | |
Wu et al. [102] | A. baumannii | MDR | Non-MDR | Total hospital cost | Median (Q) | 24,897(156940) | 8823(63540) | 16,074(93390) | 2.82 | < 0.01 |  |  |  |  |  |  |
Guo et al. [103] | A. baumannii | MDR | Non-MDR | Total hospital cost | Median (IQR) | 10,452(4742–21,484) | 3759(1586–9310) | 6693(3156–12,174) | 2.78 | < 0.001 | Mean (SD) | 14,087(12302) | 12,302(11045) | 6638(1257) | 1.89 | < 0.001 |
Xu et al. [51] | A. baumannii | MDR | Non-MDR | Total hospital cost | Â | Â | Â | Â | Â | Â | Mean (SD) | 5446(6481) | 6481(3602) | 2347(2879) | 1.76 | 0.0250 |
A. baumannii | MDR | Non-MDR | Antibiotic cost | Â | Â | Â | Â | Â | Â | Mean (SD) | 222(267) | 267(166) | Â | Â | 0.0540 | |
Lee et al. [104] | A. baumannii | MDR | Non-MDR | Total hospital cost | Â | Â | Â | Â | Â | Â | Mean (SD) | 12,515(8465) | 8465(5375) | 6003(3090) | 1.92 | 0.0010 |
A. baumannii | MDR | Non-MDR | Antibiotic cost | Â | Â | Â | Â | Â | Â | Mean (SD) | 3021(1822) | 1822(1760) | 866(62) | 1.40 | 0.0140 | |
Thatrimontrichai et al. [105] | A. baumannii | CRAB | CSAB | Total hospital cost | Median (range) | 11,785(2176–45,664) | 9745(5266–24,170) |  |  | > 0.05 |  |  |  |  |  |  |
A. baumannii | CRAB | Without infection | Total hospital cost | Median (range) | 11,785(2176–45,664) | 7806(3877–33,608) |  |  | > 0.05 |  |  |  |  |  |  | |
Young et al. [106] | A. baumannii | MDR | Without infection | Total hospital charge |  |  |  |  |  |  | Mean | 372,424 | 165,032 | 207,392 | 2.26 | < 0.001 |
A. baumannii | MDR | Without infection | Total hospital charge |  |  |  |  |  |  | Mean |  |  | 73,924 |  | < 0.05 | |
Wilson et al. [107] | A. baumannii | MDR | Without infection | Total hospital cost |  |  |  |  |  |  | Mean (SD) | 269,823(215236) | 215,236(156080) | 131,961(59155) | 1.96 | < 0.01 |