Molecular epidemiological analysis and risk factors for acquisition of carbapenemase-producing Enterobacter cloacae complex in a Japanese university hospital

Table 2 Culture source, clinical diagnosis, and outcome among carbapenem-resistant Enterobacter cloacae complex cases

	CREC (n = 39)		OR (95% CI)	p
	CPEC (n = 20)	Non-CPEC (n = 19)	OR (95% CI)	p
Culture source
Sterile site	2	3
Blood	1	2	0.46 (0.007–9.51)	0.605
Abscess	1	0		1
Vascular graft	0	1		0.487
Non-sterile site	18	16
Sputum	11	4	4.40 (0.94–25.0)	0.048
Peritoneal fluid (not punctured)	2	4	0.43 (0.03–3.46)	0.407
Urine	1	3	0.29 (0.05–4.02)	0.342
Bile	1	2	0.46 (0.007–9.51)	0.605
Oral swab	0	1		0.487
Stool	2	3	0.60 (0.04–5.96)	0.661
Clinical diagnosis
Colonisation	11	7	2.06 (0.49–9.17)	0.341
Infection	9	12
Pneumonia	5	2	2.76 (0.38–33.1)	0.407
Peritonitis	1	5^a	0.15 (0.003–1.60)	0.092
Pyelonephritis	0	3		0.106
Bacteremia	1	2^a	0.46 (0.007–9.51)	0.605
Cholangitis	1	0		1
Vascular graft infection	0	1		0.487
Abscess	1	0		1
Outcome
Required intensive care unit stay in the 7 days after positive culture	10	7	1.67 (0.40–7.48)	0.523
Died at the end of the 30-day evaluation	1	2	0.46 (0.007–9.51)	0.605
Among sterile site positive culture	0	1
Among non-sterile site positive culture	1	1
Died during hospitalisation	3	2	1.48 (0.15–19.9)	1
Among sterile site positive culture	1	1
Among non-sterile site positive culture	2	1

^aOne case had peritonitis with bacteremia
Note. OR Odds ratio, CI Confidence interval, CREC Carbapenem-resistant Enterobacter cloacae complex, CPEC Carbapenemase-producing Enterobacter cloacae complex

ISSN: 2047-2994