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Table 1 Model inputs by treatment alternatives

From: A cost-effectiveness analysis of mupirocin and chlorhexidine gluconate for Staphylococcus aureus decolonization prior to hip and knee arthroplasty in Alberta, Canada compared to standard of care

Variable

Usual Care (No decolonization)

Decolonization Bundle

Ranges for Inputs (95% CI unless otherwise stated)

Source

Distribution for PSA

Risk of S.aureus complex SSI

0.40%

 

0.338–0.464

AHS IPC Database

Beta

Risk of other complex SSI

0.64%

0.64%

0.576–0.703

AHS IPC Database

Beta

RR for S.aureus SSI with decolonization bundle

 

0.51

0.3–0.85

Schweizer et al. [13]

Beta

Mupirocin Cost/ person ($)a

0

2.30

1.15–3.45

Alberta Blue Cross Formulary

Gamma

Chlorhexidine Cost/person ($)a

0

4.95

2.47–7.43

Dufort Lavigne Website [16]

Gamma

Cost of Nurse Educator/ person ($)a

0

13.35

6.68–20.03

AHS Job Posting for Infection Control Professional

Gamma

1 year costs SSI with S. aureus($)

108,175

108,175

88,223-128,127

Rennert-May et al. [15]

Gamma

1 year costs SSI with other pathogen($)

87,317

87,317

79,830-94,804

Rennert-May et al. [15]

Gamma

1 year costs with no infection ($)

19,893

19,893

11,216-28,570

Rennert-May et al. [15]

Gamma

  1. Abbreviations: SSI Surgical Site Infection, AHS Alberta Health Services, IPC Infection Prevention and Control, S.aureus Staphylococcus aureus, PSA Probabilistic sensitivity analysis, RR rate ratio
  2. aRanges for cost created by adding and subtracting 50%