Table 4 Univariate and multivariate analysis of risk factors for treatment failure in organ-space SSI-CRAN

Male, n (%)

232

(46)

42

(46.2)

1

0.86

0.52–1.43

0.57

Mean age, years (SD)

53.1

(14.3)

51.4

(15.3)

0.26

0.99

0.97–1.01

0.33

  > 65 years (%)

129

(25.6)

19

(20.9)

0.36

Urgent surgery, n (%)

66

(13.1)

13

(14.3)

0.74

 Intrinsic tumour, n (%)

203

(40.3)

31

(34.1)

0.29

 Extrinsic tumour, n (%)

97

(19.2)

26

(28.6)

0.05

1.71

0.91–3.24

0.09

 Epilepsy, n (%)

23

(4.6)

0

(0)

0.03

0

0

0.99

 Vascular, n (%)

130

(25.8)

22

(24.2)

0.79

 Trauma, n (%)

14

(2.8)

3

(3.3)

0.73

 Others, n (%)

37

(7.3)

9

(9.9)

0.39

 Supratentorial, n (%)

386

(76.6)

63

(69.2)

0.15

 Infratentorial, n (%)

49

(9.7)

13

(14.3)

0.19

 Retromastoid, n (%)

69

(13.7)

15

(27.5)

0.51

Duration of surgery, minutes (SD)

255.2

(99.6)

265.9

(111.4)

0.65

  > P75^a, n (%)

124

(24.6)

28

(30.8)

0.57

Mean hospital stay, median (range)

7

(5–13)

7

(5–31)

0.59

CHARLSON, mean (SD)

3.14

(2.3)

3.03

(2.2)

0.70

0.90

0.78–1.05

0.20

  < 3, n (%)

245

(48.6)

47

(51.6)

0.65

 3–5, n (%)

184

(36.5)

30

(33)

0.55

 6–8, n (%)

56

(11.1)

13

(14.3)

0.38

  > 9, n (%)

19

(3.8)

1

(1.1)

0.34

ASA^b, mean (SD)

2.3

(0.7)

2.4

(0.8)

0.08

 ASA > 2, n (%)

179

(35.5)

44

(48.4)

0.025

2.26

1.32–3.87

0.003

NNIS^c, mean (SD)

0.9

(0.7)

1

(0.7)

0.24

 NNIS I-II, n (%)

372

(73.8)

69

(75.8)

0.79

 Appropriate, n (%)

432

(85.7)

80

(87.9)

0.74

 Inappropriate, n (%)

59

(11.7)

11

(12.1)

0.86

 Non registered, n (%)

13

(2.6)

0

(0)

0.23

Metal plates, n (%)

465

(92.3)

78

(85.7)

0.06

1.8

0.84–3.87

0.13

Use of steroids/chemotherapy, n (%)

369

(73.2)

70

(76.9)

0.52

Re-intervention, n (%)

97

(19.2)

61

(67)

< 0.001

8.93

5.33–14.96

< 0.001

ICP^d sensor, n (%)

30

(6)

6

(6.6)

0.81

CSF^e leak, n (%)

7

(1.4)

4

(4.4)

0.72

0.85

0.21–3.44

0.82

Mortality 30d post surgery, n (%)

31

(6.2)

2

(2.2)

0.21