Table 2 MIC and FIX values of colistin in combination with antifungals from the checkerboard assay
From: In vitro polymyxin activity against clinical multidrug-resistant fungi
Strains tested | Agents in combination | MIC alone (μg/ml) | MIC in the combination (μg/ml) | FIC | FIX | Outcome |
|---|---|---|---|---|---|---|
Rhodotorula mucilaginosa | Colistin | 16 | 1 | 0.06 | 0.5 | Synergy |
Fluconazole | 128 | 64 | 0.5 | |||
Candida albicans H5 | Colistin | 128 | 1 | 0.007 | 1 | Additivity |
Fluconazole | 16 | 16 | 1 | |||
Candida albicans H6 | Colistin | 128 | 64 | 0.5 | 0.5 | Synergy |
Itraconazole | 32 | 2 | 0.06 | |||
Colistin | 128 | 1 | 0.007 | 0.5 | Synergy | |
Amphotericin B | 1 | 0.5 | 0.5 | |||
Lichtheimia corymbifera ST87 | Colistin | 32 | 0.5 | 0.01 | 0.2 | Synergy |
Itraconazole | 2 | 0.5 | 0.25 | |||
Colistin | 32 | 0.5 | 0.01 | 0.2 | Synergy | |
Amphotericin B | 2 | 0.5 | 0.25 |