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Table 2 Patient characteristics and outcome by adherence or non-adherence to guidelines

From: The association between adherence to national antibiotic guidelines and mortality, readmission and length of stay in hospital inpatients: results from a Norwegian multicentre, observational cohort study

 

Non-adherence (N = 667)

Adherence (N = 1089)

P-value

Patient characteristics

 Indication for treatment

  LRTI

161 (24.1)

372 (34.2)

< 0.001

  COPD with LRTI

124 (18.6)

230 (21.1)

 

  Sepsis

111 (16.6)

180 (16.5)

 

  SSTI

72 (10.8)

115 (10.6)

 

  GI-infection

44 (6.6)

34 (3.1)

 

  UTI

80 (12.0)

99 (9.1)

 

  Other infections

75 (11.2)

59 (5.4)

 

 Charlson Comorbidity Index

  CCI = 0

240 (36.0)

432 (39.7)

0.083

  CCI = 1

212 (31.8)

373 (34.3)

 

  CCI = 2

119 (17.8)

141 (13.0)

 

  CCI = 3

45 (6.8)

65 (6.0)

 

  CCI = 4

24 (3.6)

33 (3.0)

 

  CCI > 4

27 (4.1)

45 (4.1)

 

 Age, mean (std.dev.)

67.3 (18.2)

67.4 (19.1)

0.885

 Age

  <=45

92 (13.8)

161 (14.8)

0.680

  46–65

156 (23.4)

240 (22.0)

 

  66–85

320 (48.0)

508 (46.7)

 

  >85

99 (14.8)

180 (16.5)

 

 Admitted from institution

120 (18.0)

135 (12.4)

0.001

 Discharged to institution

182 (29.0)

258 (24.4)

0.090

 Sex

  Male

352 (52.8)

565 (51.9)

0.717

  Female

315 (47.2)

524 (48.1)

 

 Outcome

  In-hospital mortality

38 (5.7)

32 (2.9)

0.004

  30-day mortality

75 (11.2)

67 (6.2)

< 0.001

  30-day readmission (n = 623/1047)

140 (22.5)

206 (19.7)

0.173

  LOSa, mean (std.dev.) (n = 623/1047)

7.3 (4.4)

6.7 (4.1)

0.004

  1. aLOS = Length of stay. All analysis was performed using chi-square tests, except mean age and LOS which were analysed using two-sample t-test. P-values in boldface are statistically significant (<0.05)