Antibiotic | E. coli | Klebsiella spp | ||||||
---|---|---|---|---|---|---|---|---|
2011/2013 N (%S) | 2015/2016 N (%S) | OR (95%CI) | P | 2011/2013 N (%S) | 2015/2016 N (%S) | OR (95% CI) | P | |
Amikacin | 29,667 (97%) | 41,818 (90%) | 0.29 (0.26–0.3) | 0.0001 | 7768 (96%) | 9498 (94%) | 0.65 (0.57–0.75) | 0.0001 |
Amoxicillin/clavulanic acid | 30,411 (61%) | 39,116 (59%) | 1.13 (1.10–1.17) | 0.0001 | 7883 (67%) | 9069 (62%) | 0.80 (0.75–0.86) | 0.0001 |
Ampicillin | 22,985 (23%) | 35,906 (24%) | 1.06 (1.02–1.10) | 0.01 | – | – | – | – |
Aztreonam | 27,221 (66%) | 40,029 (57%) | 0.65 (0.63–0.67) | 0.0001 | 7020 (69%) | 7924 (65%) | 0.83 (0.78–0.90) | 0.0001 |
Cefepime | 26,314 (74%) | 40,524 (62%) | 0.60 (0.58–0.62) | 0.0001 | – | – | – | – |
Cefoxitin | 23,858 (87%) | 33,104 (76%) | 0.47 (0.45–0.50) | 0.0001 | 5853 (89%) | 6373 (83%) | 0.60 (0.54–0.67) | 0.0001 |
Ceftazidime | 28,730 (71%) | 41,816 (62%) | 0.73 (0.71–0.76) | 0.0001 | 7335 (71%) | 9498 (64%) | 0.73 (0.68–0.78) | 0.0001 |
Ceftriaxone | 20,059 (64%) | 41,816 (58%) | 0.85 (0.82–0.88) | 0.0001 | 4750 (65%) | 9498 (63%) | 0.92 (0.85–0.99) | 0.02 |
Cefuroxime | 24,662 (59%) | 33,106 (56%) | 0.96 (0.93–0.99) | 0.02 | 6516 (64%) | 6579 (61%) | 0.88 (0.82–0.94) | 0.0004 |
Ciprofloxacin | 29,411 (55%) | 40,524 (57%) | 1.22 (1.19–1.26) | 0.0001 | 7883 (73%) | 9311 (71%) | 0.91 (0.85–0.97) | 0.004 |
Gentamicin | 29,327 (72%) | 41,818 (72%) | 1.00 (0.98–1.03) | 1 | 7601 (75%) | 9498 (78%) | 1.18 (1.10–1.27) | 0.0001 |
Imipenem | 30,411 (99%) | 41,813 (97%) | 0.33 (0.29–0.37) | 0.0001 | 7883 (98%) | 9498 (96%) | 0.49 (0.41–0.60) | 0.0001 |
Nitrofurantoin | 18,422 (96%) | 29,434 (87%) | 0.28 (0.26–0.30) | 0.0001 | 4356 (52%) | 5155 (59%) | 1.33 (1.22–1.44) | 0.0001 |
Piperacillin/tazobactam | 28,739 (83%) | 40,524 (76%) | 0.84 (0.81–0.873) | 0.0001 | 7618 (81%) | 9292 (78%) | 0.83 (0.77–0.90) | 0.0001 |
Tigecycline | 9716 (98%) | 39,050 (96%) | 0.24 (0.20–0.30) | 0.0001 | 2243 (87%) | 8546 (93%) | 1.99 (1.71–2.31) | 0.0001 |
Trimethoprim/sulfamethoxazole | 29,689 (49%) | 41,496 (53%) | 1.13 (1.10–1.16) | 0.0001 | 7709 (57%) | 9498 (58%) | 1.04 (0.98–1.11) | 0.2 |