Year | Mutation in the 23S rRNA | Isolates number | MLVA genotype (Numbers) | No. of “AGT” VNTRs repeats in p1 gene (Number) | MIC (μg/ml) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
type1 | type2 | type1 | type2 | type1 | type2 | ERY | AZM | LVX | TET | ||
2014 | A2063G | 13 | 2 | 4/5/7/2 (10) 4/5/7/3 (2) 4/4/7/2 (1) | 3/5/6/2 (2) | 5 repeats(1) 7 repeats(6) 8 repeats(5) 11repeats(1) | 6 repeats(1) 8 repeats(1) | ≥256 | 2–32 | 0.25–1 | 0.016–0.25 |
A2064G | 1 | 0 | 4/5/7/2 (1) | 0 | 7 repeats(1) | ≥256 | 4 | 0.25 | 0.032 | ||
None | 2 | 9 | 4/5/7/2 (2) | 3/5/6/2 (9) | 5 repeats(1) 7 repeats(1) | 6 repeats(3) 7 repeats(2) 8 repeats(3) 12 repeats(1) | ≤0.008 | ≤0.008 | 0.25–1 | 0.032–0.25 | |
2015 | A2063G | 12 | 2 | 4/5/7/2 (12) | 3/5/6/2 (2) | 4 repeats(1) 6 repeats(5) 7 repeats(4) 8 repeats(2) | 8 repeats(2) | ≥256 | 2–64 | 0.125–0.5 | 0.032–0.5 |
None | 0 | 5 | 0 | 3/5/6/2 (5) | 0 | 5 repeats(1) 8 repeats(4) | ≤0.008 | ≤0.008 | 0.25–1 | 0.032–0.25 | |
2016 | A2063G | 19 | 4 | 4/5/7/2 (17) 4/5/7/3 (2) | 3/5/6/2 (3) 3/5/7/2 (1) | 6 repeats(2) 7 repeats(5) 8 repeats(4) 9 repeats(6) 10 repeats(1) 12 repeats(1) | 7 repeats(3) 10 repeats(1) | ≥256 | 2–64 | 0.125–1 | 0.016–0.5 |
None | 0 | 12 | 0 | 3/5/6/2 (11) 3/5/7/2 (1) | 0 | 6 repeats(2) 7 repeats(5) 8 repeats(3) 10 repeats(1) 14 repeats(1) | ≤0.008 | ≤0.008 | 0.25–1 | 0.032–0.5 |