Fig. 1

Odds ratio for resistance to empiric therapy related to time since the last drug resistant pathogen (DRP) was cultured. Legend. M = months. C-2GC + AG = Combination 2nd generation cephalosporin and aminoglycoside. Prior-DRP = drug resistant pathogen(s) isolated from any body site: Vancomycin resistant enterococci, multi resistant Staphylococcus aureus, Enterobacteriaceae with in vitro resistance to aminoglycosides, second and/or third generation cephalosporin’s (including ESBL positive Enterobacteriaceae) and/or quinolones, Pseudomonas aeruginosa with resistance to third generation cephalosporin’s, aminoglycosides or quinolones. Odds ratio for infection with cefuroxime and gentamicin resistant Gram-negative pathogen, for patients with prior-DRP isolated compared to patients without prior-DRP isolates, for different time intervals in months since the last DRP was cultured. Note that the y-axis is on a logarithmic scale