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Table 1 Sensitivities and specificities of the five methods utilized for S. aureus detection in ETA samples compared to the extended gold standard

From: Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples

  Extended gold standard* Sensitivity (%) Specify (%)
+ (95% C1) (95% C1)
GeneXpert + 41 0 100 100
0 38
Q-culture + 41 2 100 94.74
0 36 (82.25–99.36)
Enrichment + 41 3 100 92.11
0 35 (78.62–98.34)
qPCR + 41 18 100 52.63
0 20 (35.82–69.02)
SQ-culture + 39 0 95.12 100
2 38 (83.47–99.40)
  1. *S. aureus detected by SQ-culture plus two samples that showed S. aureus presence by the other four methods but not by standard culture