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Table 1 Sensitivities and specificities of the five methods utilized for S. aureus detection in ETA samples compared to the extended gold standard

From: Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples

 

Extended gold standard*

Sensitivity (%)

Specify (%)

+

(95% C1)

(95% C1)

GeneXpert

+

41

0

100

100

0

38

Q-culture

+

41

2

100

94.74

0

36

(82.25–99.36)

Enrichment

+

41

3

100

92.11

0

35

(78.62–98.34)

qPCR

+

41

18

100

52.63

0

20

(35.82–69.02)

SQ-culture

+

39

0

95.12

100

2

38

(83.47–99.40)

  1. *S. aureus detected by SQ-culture plus two samples that showed S. aureus presence by the other four methods but not by standard culture