| 7% discount rate, 10% effectiveness | 3% discount rate, 10% effectiveness | 7% discount rate, 50% effectiveness | 3% discount rate, 50% effectiveness |
---|---|---|---|---|
Total Intervention Costs (in billions) | $3.7 | $4.7 | $3.3 | $4.2 |
Total Benefits (in billions) | ||||
Direct Medical Cost Savings | ||||
  Savings in Patient Care Costs | $1.5 | $1.8 | $7.6 | $9.1 |
  Savings in Hospital Expenditures for Antibiotics | $3.8 | $4.2 | $3.8 | $4.2 |
Benefits of Morbidity Risk Reduction | ||||
  Low $/Lost QALY from HCA-CDI | $0.4 | $0.3 | $2.1 | $1.3 |
  Central $/ Lost QALY from HCA-CDI | $0.8 | $0.6 | $4.1 | $2.8 |
  High $/ Lost QALY from HCA-CDI | $1.3 | $0.8 | $6.3 | $4.2 |
Benefits of Mortality Risk Reduction | ||||
 Low VSL | ||||
  35% Attributable Mortality Proportion | $22.1 | $26.6 | $111.2 | $133.2 |
  50% Attributable Mortality Proportion | $31.5 | $38.0 | $157.7 | $190.2 |
 Central VSL | ||||
  35% Attributable Mortality Proportion | $46.6 | $56.2 | $232.8 | $280.8 |
  50% Attributable Mortality Proportion | $66.5 | $80.2 | $332.6 | $401.1 |
 High VSL | ||||
  35% Attributable Mortality Proportion | $71.1 | $85.7 | $355.7 | $428.7 |
  50% Attributable Mortality Proportion | $102.7 | $122.5 | $507.8 | $612.5 |
Range of Total Net Benefits | ||||
  Low | $24.1 - $33.5 | $28.2 - $ 39.6 | $121.4 - $167.9 | $143.6 - $200.6 |
  Central | $49.0 - $68.9 | $58.1 - $ 82.1 | $245.0 - $344.8 | $292.7 - $413.0 |
  High | $74.0 - $105.6 | $87.8 - $124.6 | $370.1 - $522.2 | $442.0 - $625.8 |