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Table 1 Distribution of third generation cephalosporin resistant Enterobacteriaceae (3GCREB) infections in the ATHOS project, 2014–2015, Germany

From: Incidence of infections due to third generation cephalosporin-resistant Enterobacteriaceae - a prospective multicentre cohort study in six German university hospitals

Parameter

Category

3GCREB infections

n (%)

3GCREB CAI

n (%)

3GCREB HAI

n (%)

3GCREB

total

3370 (100%)

1596 (100%)

1774 (100%)

Species

E. coli

1624 (48%)

910 (57%)

714 (40%)

Enterobacter spp.

702 (21%)

221 (14%)

481 (27%)

Klebsiella spp.

562 (17%)

264 (17%)

298 (17%)

Citrobacter spp.

209 (6%)

76 (5%)

133 (7%)

Other species a

273 (8%)

125 (8%)

148 (8%)

Resistance

all 3GCREB

   

 only 3GCR

1488 (44%)

580 (36%)

908 (51%)

 + FQR

1796 (53%)

979 (61%)

817 (46%)

 + CR

86 (3%)

37 (2%)

49 (3%)

E. coli

1624 (100%)

910 (100%)

714 (100%)

 only 3GCR

409 (25%)

209 (23%)

200 (28%)

 + FQR

1203 (74%)

698 (77%)

505 (71%)

 + CR

12 (1%)

3 (0%)

9 (1%)

Enterobacter spp.

702 (100%)

221 (100%)

481 (100%)

 only 3GCR

553 (79%)

168 (76%)

385 (80%)

 + FQR

122 (17%)

45 (20%)

77 (16%)

 + CR

27 (4%)

8 (4%)

19 (4%)

Klebsiella spp.

562 (100%)

264 (100%)

298 (100%)

 only 3GCR

157 (28%)

59 (22%)

98 (33%)

 + FQR

362 (64%)

181 (69%)

181 (61%)

 + CR

43 (8%)

24 (9%)

19 (6%)

Infections

SSI

401 (12%)

99 (6%)

302 (17%)

UTI

1528 (45%)

872 (55%)

656 (37%)

LRTI

571 (17%)

158 (10%)

413 (23%)

BSI

459 (14%)

220 (14%)

239 (13%)

Other infections b

411 (12%)

247 (15%)

164 (9%)

Year

2014

1784 (53%)

847 (53%)

937 (53%)

2015

1586 (47%)

749 (47%)

837 (47%)

Ward type

General ward

2174 (65%)

1102 (69%)

1072 (60%)

ICU/interm. Care

1196 (35%)

494 (31%)

702 (40%)

Specialty

Surgical

1407 (42%)

522 (33%)

885 (50%)

Non-surgical

1963 (58%)

1074 (67%)

889 (50%)

  1. 3GCREB infections among 578,420 patient admissions and 3,385,112 patient days in six German university hospitals. a “Other Enterobacteriaceae species” include Cedecea, Hafnia, Morganella, Pantoea, Proteus, Providencia, Raoultella, and Serratia species. b “Other infections” includes all other infection types. 3GCREB = third generation cephalosporin-resistant Enterobacteriaceae, 3GCR third generation cephalosporin resistance, FQR fluoroquinolone resistance, CR carbapenem resistance, CA community-acquired, HA hospital-acquired, SSI surgical site infection, UTI urinary tract infection, LRTI lower respiratory tract infection, BSI bloodstream infection, ICU intensive care unit, interm. Care intermediate care. Column percentages were calculated for each parameter with respect to “3GCREB total”