Association between antibiotic consumption and the rate of carbapenem-resistant Gram-negative bacteria from China based on 153 tertiary hospitals data in 2014

Table 2 Correlations between main classes of antibiotics consumption intensity and the rate of carbapenem-resistant in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii

Classes (ATC category)	Correlation
	E. coli		K. pneumoniae		P. aeruginosa		A. baumannii
	r ^a	p*	r	p	r	p	r	p
All antibiotics (J01)	0.093	0.324	−0.005	0.954	0.061	0.484	0.075	0.416
β-Lactams (J01C + J01D)	0.138	0.141	0.018	0.839	0.021	0.811	0.104	0.260
Penicillins (J01C)	0.121	0.198	−0.041	0.639	−0.044	0.608	−0.104	0.256
Cephalosporins (J01DB + J01 DC + J01DD + J01DE)	0.039	0.676	−0.037	0.678	−0.070	0.417	0.154	0.093
The third generation cephalosporin (J01DD)	0.024	0.803	0.004	0.961	0.000	0.996	0.132	0.151
The fourth generation cephalosporin (J01DE)	−0.080	0.393	0.064	0.471	0.143	0.097	−0.049	0.596
Carbapenems (J01DH)	0.271*	0.003	0.427*	<0.01	0.463*	<0.01	0.331*	<0.01
Fluoroquinolones (J01MA)	−0.004	0.966	0.046	0.600	0.129	0.134	0.073	0.431

^ar denotes pearson’s correlation coefficient; *statistically significant association (p < 0.05)

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