Appendix 2 Univariate analysis of factors associated with development of SSI
From: Optimal timing of surgical antimicrobial prophylaxis in laparoscopic surgery: a before-after study
Variables | No SSI n = 1207 | SSI n = 190 | P value |
|---|---|---|---|
Age, median, (IQR) years | 66 (52–75) | 70 (60–77) | 0.001 |
< 65, n (%) | 554 (45.9) | 71 (37.4) | 0.028 |
≥ 65, n (%) | 653 (54.1) | 119 (62.6) | |
Male gender, n (%) | 532 (44.1) | 74 (39.0) | 0.19 |
Co-morbidities, n (%) | |||
Diabetes mellitus | 164 (13.6) | 28 (14.7) | 0.67 |
Chronic lung diseases | 57 (4.7) | 12 (6.3) | 0.35 |
Cardiovascular diseases | 59 (4.9) | 10 (5.3) | 0.83 |
Hypertension | 442 (36.6) | 71 (37.4) | 0.84 |
Dyslipidemia | 198 (16.4) | 33 (17.4) | 0.74 |
Current smoker, n (%) | 560 (46.4) | 110 (47.9) | 0.003 |
ASA score, n (%) | |||
1 no disturbance | 250 (20.7) | 29 (15.3) | Ref. |
2 mild disturbance | 854 (70.8) | 144 (75.8) | 0.08 |
3 severe disturbance | 99 (8.2) | 17 (9.0) | 0.23 |
4 life-threatening | 4 (0.3) | 0 (0) | N/A |
Wound class, n (%) | |||
2 clean-contaminated | 1202 (99.6) | 188 (99.0) | 0.25 |
3 contaminated | 5 (0.4) | 2 (1.1) | 0.25 |
Emergent surgery, n (%) | 200 (16.6) | 22 (11.6) | 0.080 |
Type of surgery, n (%) | |||
Cholecystectomy | 291 (24.1) | 16 (8.4) | Ref. |
Gastrectomy | 294 (24.4) | 77 (40.5) | < 0.001 |
Appendectomy | 140 (11.6) | 17 (9.0) | 0.029 |
Colectomy | 175 (14.5) | 25 (13.2) | 0.004 |
Proctectomy | 306 (25.4) | 55 (29.0) | < 0.001 |
Cholecystectomy and appendectomy | 1 (0.1) | 0 (0) | N/A |
Operation time, median, (IQR) min | 205 (131–285) | 273 (197–337) | < 0.001 |
< 180, n (%) | 502 (41.6) | 42 (22.1) | |
≥ 180, n (%) | 705 (58.4) | 148 (77.9) | < 0.001 |
SAP drip infusion time, median, (IQR) min | 18 (14–23) | 18 (14–24) | 0.97 |
Time from SAP completion to surgical incision, median, (IQR) min | 12 (4–25) | 15 (3–31) | 0.37 |
31–60 min | 175 (14.5) | 42 (22.2) | Ref. |
< 0 min | 143 (11.9) | 23 (12.2) | 0.16 |
0–30 min | 861 (71.4) | 119 (63.0) | 0.005 |
> 60 min | 26 (2.2) | 6 (3.2) | 0.52 |
Intervention status, “yes” | 395 (32.7) | 60 (31.6) | 0.75 |