Skip to main content

Table 1 Comparisons of demographic and clinical variables of adult orthopaedic implant patients with future surgical site infections resistant to the prophylactic regimen of the index surgery versus prophylaxis-susceptible surgical site implant infections

From: Should antibiotic prophylaxis before orthopedic implant surgery depend on the duration of pre-surgical hospital stay?

 

Susceptible to prior prophylaxis

 

Resistant to prior prophylaxis

Total n = 611

n = 304

p value*

n = 307

Female sex

118 (39%)

0.752

123 (40%)

Age (median)

67 years

0.097

62 years

Past history of MRSAb body carriage

12 (4%)

0.002

32 (10%)

Immune suppressiona

91 (30%)

0.030

70 (23%)

- diabetes mellitus

45 (15%)

0.045

28 (9%)

Shoulder implants

12 (4%)

0.235

7 (2%)

Arthroplasties

147 (48%)

0.275

162 (53%)

Spondylodeses

14 (5%)

0.600

17 (6%)

Plates

66 (22%)

0.575

61 (20%)

Intramedullary nails

20 (7%)

0.376

26 (8%)

Foot osteosyntheses

15 (5%)

0.295

10 (3%)

Duration of prior hospital stay (median)

1 day (range, 0–178 d)

0.408

1 day (range, 0–68 d)

  1. *Significant p values ≤0.05 are displayed in bold and italic
  2. aImmune suppression = diabetes mellitus, corticosteroid medication, organ transplantation, cirrhosis CHILD C, dialysis, or active cancer
  3. bMethicillin-resistant Staphylococcus aureus