Risk factors for poor outcome in community-onset Clostridium difficile infection

Table 1 Risk factors for poor outcome in community-onset Clostridium difficile infection in multivariate logistic regression analyses

Variable	Odds ratio	95% CI	P
Age > 70 y	1.47	0.468–4.627	0.51
Male	2.74	0.998–7.525	0.05
Long-term care facility residence	0.98	0.287–3.354	0.98
Glasgow coma scale ≤12	2.06	0.589–7.185	0.26
Presentation with septic shock	0.84	0.256–2.742	0.77
Heart rate ≥ 100 /min	2.81	0.972–8.102	0.06
Prior proton pump inhibitor use within 1 month	3.88	1.310–11.518	0.01
ICU admission	2.71	0.599–12.257	0.20
Max leukocyte count > 20,000 /mL	2.78	0.897–8.684	0.08
Min hemoglobin level < 10 g/dL	3.55	1.230–10.219	0.02
Min bicarbonate level < 20 mmol/L	2.16	0.736–6.356	0.16
Max glucose level > 150 mg/dL	0.83	0.259–2.623	0.74
Max creatinine level > 2 mg/dL	0.54	0.160–1.841	0.33
Min albumin level < 2.5 g/dL	1.21	0.373–3.928	0.75

ICU Intensive care unit, Max maximum, Min Minimum, CI, confidence interval
Poor outcome was defined if at least one of following event was occurred: 1) all-cause 30-day mortality, 2) in-hospital mortality, or 3) surgery due to C. difficile infection
Clinical variables (n-152) and laboratory variables (n = 151) were analyzed in two separated models in consideration of potential collinearity
Laboratory results were the most deviated value from normal range within 24 h after admission

ISSN: 2047-2994