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Table 1 Cross-correlation coefficients between antibiotic use and respiratory viruses (2010-2015)

From: Temporal relationship between antibiotic use and respiratory virus activities in the Republic of Korea: a time-series analysis

Antibiotics RSV IFV hCoV hRV ADV
Tetracyclines −0.14
p = 0.24
0-month lag
0.05
p = 0.67
7-month lag
−0.09
p = 0.43
− 3-month lag
0.24
p = 0.04
2-month lag
− 0.07
p = 0.55
0-month lag
Penicillins − 0.01
p = 0.98
10-month lag
0.45
p < 0.01
0-month lag
0.06
p = 0.64
2-month lag
−0.13
p = 0.29
2-month lag
− 0.09
p = 0.44
6-month lag
Other beta-lactam antibacterials −0.02
p = 0.90
1-month lag
0.46
p < 0.01
0-month lag
0.02
p = 0.85
1-month lag
−0.14
p = 0.24
2-month lag
−0.11
p = 0.34
0-month lag
Macrolides 0.12
p = 0.31
10-month lag
0.40
p < 0.01
0-month lag
−0.06
p = 0.60
1-month lag
−0.08
p = 0.50
8-month lag
− 0.16
p = 0.18
9-month lag
Aminoglycosides −0.03
p = 0.79
10-month lag
0.15
p = 0.20
0-month lag
0.11
p = 0.36
1-month lag
0.10
p = 0.39
0-month lag
−0.11
p = 0.37
5-month lag
Fluoroquinolones −0.02
p = 0.84
3-month lag
0.35
p < 0.01
0-month lag
−0.03
p = 0.83
2-month lag
−0.04
p = 0.76
2-month lag
− 0.16
p = 0.19
6-month lag
  1. Abbreviations: ADV adenovirus, hCoV human coronavirus, hRV human rhinovirus, IFV Influenza virus, RSV respiratory syncytial virus
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