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Table 1 Characteristics of patients receiving antibiotic prophylaxis with ceftriaxone and ampicillin (n = 4149)

From: The efficacy of ampicillin compared with ceftriaxone on preventing cesarean surgical site infections: an observational prospective cohort study

Characteristic

Ceftriaxone (n = 911)

Ampicillin (n = 3238)

p-value

 

n

%

n

%

 

Age (yr)

  < 20

24

2.6

209

6.5

 

 20–34

691

75.9

2391

73.8

 

  ≥ 35

196

21.5

638

19.7

 

 Mean ± SD

30.2

±5.3

28.9

±6.2

< 0.001

Ethnic minority

130

14.3

1788

55.2

< 0.001

Education level

 None

88

9.7

1513

46.7

< 0.001

 Primary

99

10.9

598

18.5

 

 Intermediate

236

25.9

673

20.8

 

 College/higher

488

53.5

454

14.0

 

Antenatal care

 No

3

0.3

72

2.2

< 0.001

 Camp

40

4.4

827

25.5

 

 Hospital

868

95.3

2339

72.3

 

Body weight (kg)

  ≥ 80

155

17.0

408

12.6

 

 Mean ± SD

69.0

±11.7

65.4

±12.4

< 0.001

Hb (g/dL)

  < 11

145

15.9

617

19.1

 

 Mean ± SD

11.5

±1.0

11.4

±1.2

0.008

HIV positive

5

0.6

124

3.8

< 0.001

Referral

48

5.3

1070

33.1

< 0.001

Gravida

     

Primigravida

308

33.8

1140

35.2

 

Median (IQR)

2

(1–2)

2

(1–3)

0.002

Multiple gestations

13

1.4

123

3.8

< 0.001

GA (weeks)

  < 37

26

2.9

425

13.1

 

 Mean ± SD

38.6

±1.3

38.4

±2.4

0.152

PV ≥5 occasions before surgery

17

1.9

405

12.5

< 0.001

Amniotic fluid

 Clear

896

98.4

2757

85.2

< 0.001

 MSAF

11

1.2

468

14.4

 

 Foul smelling

4

0.4

13

0.4

 

ROM duration (hr)

 Median (IQR)

0

(0–0)

0

(0–2.3)

< 0.001

Fetal death

5

0.6

38

1.2

0.136

ASA score ≥ 3

19

2.1

198

6.1

< 0.001

Wound class ≥3

15

1.7

364

11.2

< 0.001

Operation time (min)

  ≥ 55

93

10.2

1209

37.3

 

 Median (IQR)

40

(35–45)

50

(40–60)

< 0.001

Emergency

214

23.5

2487

76.8

< 0.001

EBL (mL)

  ≥ 500

121

13.3

1956

60.4

 

 Median (IQR)

300

(300–400)

500

(400–500)

< 0.001

UTI

1

0.1

9

0.3

0.701

Skin incision line

     

 Midline

119

13.1

1492

46.1

< 0.001

 Pfannelstein

792

86.9

1746

53.9

 

Addition procedures

 Appendectomy/TR

542

59.5

1432

44.2

< 0.001

Propensity score

 Mean ± SD

0.86

±0.27

0.04

±0.11

< 0.001

 Median (IQR)

0.96

(0.92–0.96)

0.02

(0.01–0.03)

< 0.001

  1. ASA American Society of Anesthesiology, MSAF Meconium stained amniotic fluid, dL Decilitre, EBL Estimated blood loss, g Gram, GA Gestational age, Hb Hemoglobin, HIV Human immunodeficiency virus, hr. Hours, IQR Interquartile range, kg Kilogram, min Minute, PV Pelvic examinations, ROM Rupture of amniotic membranes, SD Standard deviation, SSIs Surgical site infections, TR Tubal resection, UTI Urinary tract infection, mL Millilitre, yr. Years