Table 5 Characteristics of the PMQR determinants positive Shigella flexneri isolates
Isolate number | Serotype | Year of isolation | City | Antibiotic susceptibility | Target gene mutations | PMQR determinants | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAL | NOR | gyrA | gyrB | parC | ||||||||
F12002 | 3b | 2012 | Nantong | R | R | qnrB | ||||||
F12019 | 2b | 2012 | Yangzhou | R | I | Ser83Leu | Asp87Gly | His211Tyr | Ser80Ile | aac(6′)-Ib-cr | ||
F12037 | 2a | 2012 | Zhenjiang | S | I | Ser83Leu | His211Tyr | Ser80Ile | aac(6′)-Ib-cr | |||
F12066 | 4c | 2012 | Xuzhou | R | R | Ser83Leu | His211Tyr | Ser80Ile | aac(6′)-Ib-cr | |||
F12099 | 2b | 2012 | Yangzhou | R | I | Ser83Leu | Asp87Gly | His211Tyr | Ser80Ile | Ser129Pro | aac(6′)-Ib-cr | |
F12149 | 4c | 2012 | Xuzhou | R | S | Ser83Leu | His211Tyr | Ser80Ile | Ser129Pro | aac(6′)-Ib-cr | ||
F12150 | 2a | 2012 | Xuzhou | R | I | Ser83Leu | His211Tyr | Ser80Ile | Ser129Pro | aac(6′)-Ib-cr | ||
F13055 | 4c | 2013 | Changzhou | R | R | Ser83Leu | His211Tyr | Ser80Ile | Ser129Pro | qnrS | ||
F13140 | 1a | 2013 | Yangzhou | S | S | Ser83Leu | His211Tyr | Gln517Arg | Ser80Ile | aac(6′)-Ib-cr | ||
F14054 | 2b | 2014 | Suqian | R | I | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | aac(6′)-Ib-cr, qnrS | ||
F15099 | 2a | 2015 | Taizhou | R | R | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | qnrS | ||
F15100 | 2a | 2015 | Taizhou | R | R | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | qnrS | ||
F15101 | 2a | 2015 | Taizhou | R | R | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | qnrS | ||
F15105 | 2a | 2015 | Taizhou | R | R | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | qnrS | ||
F15106 | 2a | 2015 | Taizhou | R | R | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | Ser129Pro | qnrS | |
F15107 | 2a | 2015 | Taizhou | R | R | Ser83Leu | Asp87Asn | His211Tyr | Ser80Ile | qnrS | ||