Table 2 Mutations in gyrA, gyrB and parC genes in Shigella flexneri strains in the present study
Mutations | 2012 (n = 120) | 2013 (n = 114) | 2014 (n = 85) | 2015 (n = 81) | Total (n = 400) |
|---|---|---|---|---|---|
Ser83Leu | 79.2 (95) | 75.4 (86) | 75.3 (64) | 70.4 (57) | 75.5 (302) |
Asp87Asn/ Gly | 65.0 (78) | 50.9 (58) | 61.2 (52) | 50.6 (41) | 57.3 (229) |
Asp87Asn | 24.2 (29) | 24.6 (28) | 41.2 (35) | 37.0 (30) | 30.5 (122) |
Asp87 Gly | 40.8 (49) | 26.3 (30) | 20.1 (17) | 13.6 (11) | 26.8 (107) |
His211Tyr | 75.0 (90) | 74.6 (85) | 75.3 (64) | 69.1 (56) | 73.8 (295) |
Gln517Arg | 5.8 (7) | 3.5 (4) | 2.5 (2) | 0.0 (0) | 3.3 (13) |
Ser80Ile | 77.5 (93) | 75.4 (86) | 75.3 (64) | 67.9 (55) | 74.5 (298) |
Ser129Pro | 33.3 (40) | 41.2 (47) | 52.9 (45) | 24.7 (20) | 38.0 (152) |