Antimicrobial susceptibility of Clostridium difficile isolated in Thailand

Table 2 Summary MIC data for nine antimicrobials against Thai C. difficile isolates by toxin gene profile

Antimicrobial^a	Toxigenic isolates (n = 39)		A−B− isolates (n = 66)		A+B+ isolates (n = 27)		A−B+ isolates (n = 12)
Antimicrobial^a	MIC Range	MIC₅₀/MIC₉₀	MIC Range	MIC₅₀/MIC₉₀	MIC Range	MIC₅₀/MIC₉₀	MIC Range	MIC₅₀/MIC₉₀
FDX	0.008–0.25	0.06/0.25	0.004–0.25	0.06/0.25	0.015–0.25	0.12/0.25	0.008–0.06	0.03/0.06
VAN	0.25–2	1/2	0.06–2	1/1	0.25–2	1/2	0.5–2	1/1
MTZ	0.015–0.25	0.25/0.25	0.015–0.5	0.25/0.5	0.015–0.25	0.25/0.25	0.015–0.25	0.12/0.25
RFX	0.015–>16	0.03/>16	0.008–>16	0.015/0.03	0.015–0.03	0.015/0.03	0.015–>16	>16/>16
CLI	0.015–>32	8/>32	0.03–>32	8/>32	0.015–16	8/16	0.015–>32	>32/>32
ERY	0.5–>256	2/>256	0.12–>256	2/>256	0.5–2	2/2	1–>256	>256/>256
AMC	0.03–1	0.5/1	0.03–2	0.5/1	0.03–1	0.5/1	0.03–1	0.5/1
MXF	0.12–>32	2/32	0.12–>32	2/16	0.12–4	2/2	0.25–32	16/32
MEM	0.25–4	2/4	0.25–4	2/4	0.5–4	2/4	0.25–4	4/4

^a FDX fidaxomicin, VAN vancomycin, MTZ metronidazole, RFX rifaximin, CLI clindamycin, ERY erythromycin, AMC amoxicillin/clavulanate, MXF moxifloxacin, MEM meropenem. All values are shown in mg/L

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