Skip to main content

Table 1 Clinical cases of patients from whom carbapenem resistant Klebsiella pneumoniae was isolated

From: The emergence of carbapenem resistant Klebsiella pneumoniae in Malaysia: correlation between microbiological trends with host characteristics and clinical factors

Isolate

Gender/ Age (years)

Underlying diseases

Isolation site

Length of hospitalization prior to strain isolation (days)

Stay in ICU (days)

Undergone surgical procedure

Use of medical devicesa

Prior antibiotic exposure (90 days prior to strain isolation)

Empiric antibiotic

Targeted antibiotic

Colonization / Infection

In-hospital death

K/1310-23

M / 85

SOT

Blood

5

0

No

MV, Cath

XM, CI

TZP

CT

Infection

Yes

K/1311-36

M / 72

HPT

Drainage fluid

37

17

Yes

MV, Cath

CP, IPb, PM, CLX, TX, CI, TZP, VA, MPb

VA, MP

MP, CT

Infection

Yes

K/1308-12

M / 67

DM, HPT

Drainage fluid

21

0

Yes

MV, Cath

CP, MTZ

CI

IP, CT

Infection

No

K/1312-3

M / 60

DM, HPT

Urine

110

0

Yes

MV, Cath

P, TZP, IPb

XM, IP

IPd

Colonization

Yes

K/1310-33

F / 63

DM, HPT, CKD

Blood

24

0

Unknown

Cath

CFZ, TZ, VA, IPb

CT

CT

Infection

No

K/1311-35

M / 71

DM, HPT

Sputum

108

5

Yes

Unknown

VA, CI, MPb

TZ

Nil

Colonization

No

K/1312-17

F / 77

DM

Urine

16

0

Yes

Cath

CLX, AMS

CI

Nil

Colonization

No

AN9

F / 62

HPT

Urine

16

15

No

MV, Cath

CP, MTZ, AMS

TZP, IPb

IPd

Colonization

No

K/1309-5

F / 48

DM, HPT

Tissue

21

0

Yes

MV, Cath

AMS, AMC, TZP, IPb

IPb

Nil

Colonization

No

K/1310-24

F / 69

DM, HPT

Swab

155

0

Yes

MV, Cath

VA, MTZ, CT, IPc, CI, XM, TZP

VA, TZP

VA, TZP

Colonization

No

KLEB-2013-105

F / 74

SOT

Swab

10

0

Yes

MV, Cath

OTC

AMS

Nil

Colonization

No

K/1309-18

F / 74

HPT

Tracheal secretion

10

11

Yes

MV, Cath

CP, MTZ

TZP

Nile

Infection

Yes

K/1309-39

M / 60

DM, HPT, CKD

Swab

3

0

Yes

Cath

AMS

AMS

IP, CT

Infection

No

K/1304-16

M / 57

DM, HPT

Blood

12

0

Yes

Cath

CI, TX

TZP

IP, CT

Infection

No

K/1309-38

M / 62

DM, SOT

Urine

0

0

Yes

MV, Cath

CI, CP, MTZ

TX

IP, CT

Infection

Yes

K/1311-26

F / 57

DM, HPT, SOT

Blood

0

0

Unknown

Unknown

AMS, CI

TX

Nil

Colonization

No

K/1310-35

M / 60

DM, HPT

Tracheal aspirate

67

0

Yes

MV, Cath

P, TZP

Nil

Nil

Colonization

Yes

  1. M Male, F Female, SOT Solid organ tumor, DM Diabetes mellitus, HPT Hypertension, CKD Chronic kidney disease, ICU Intensive care unit, MV Mechanical ventilation, Cath catheter, Unknown patient's medical files could not be retrieved, XM Cefuroxime, CI Ciprofloxacin, TZP Piperacillin-tazobactam, CT Colistin, CP Cefoperazone, IP Imipenem, PM Cefepime, CLX Cloxacillin, TX Ceftriaxone, VA Vancomycin, MP Meropenem, MTZ Metronidazole, P Penicillin, CFZ Cefazolin, TZ Ceftazidime, AMS Ampicillin-sulbactam, AMC Amoxicillin-clavulanate, OTC Oxytetracycline
  2. amechanical ventilation and catheter; either urinary catheter, central venous catheter or drainage catheter, bcarbapenem exposure for more than 7 days, ccarbapenem exposure for 3 -7 days, dcarbapenem administered due to other infections, epatient passed away before targeted therapy was initiated