Skip to main content

Table 1 Distribution of articles reviewed on resistance due to ESBL in East Africa hospitals and common gene variants encoding for ESBL

From: Meta-analysis of proportion estimates of Extended-Spectrum-Beta-Lactamase-producing Enterobacteriaceae in East Africa hospitals

Country Year Hospital Department Population Specimen Method Species Isolates (N) ESBL (%) ESBL-Genes
Ethiopia [48] 2004 Regional aBoth Children, adults Urine, pus, sputum bDDST K. pneumoniae 57 42 cND
Ethiopia [49] 2014 University Both Children, adults Urine DDST K. pneumoniae, E. coli 183 22 ND
Ethiopia [50] 2006 University Out-patient Children Blood, stool DDST Salmonella spp 81 27 ND
Ethiopia [51] 2012 University Both Children, adults Urine, pus, wound, sputum, stool DDST E. coli 67 36 ND
Kenya [38] 2010 Not Stated Both Children, adults Urine, stool, blood DDST, PCR-Sequencing E. coli 912 27 CTX-M (78 %), SHV (3–5 %), TEM (16 %)
Kenya [30] 2007 University Both Children, adults Urine PCR-Sequencing E. coli 17 71 CTX-M-15 type ESBLs and CMY-2 AmpC
Kenya [52] 2008 University Both Children, adults Blood DDST K. pneumoniae, E. coli 359 14 ND
Kenya [37] 2012 University Both Children, adults Urine, pus, sputum, stool DDST, PCR-Sequencing K. pneumoniae, E. coli 52 89 CTX-M (88.5 %), blaSHV (25 %), TEM (34.6 %)
Rwanda [14] 2009 University Both Children, adults Urine DDST K. pneumoniae, E. coli, others 196 38 ND
Tanzania [11] 2001 University In-patients Children Blood DDST, PCR-Sequencing K. pneumoniae, E. coli 125 15 CTX-M, SHV, TEM
Tanzania [24] 2009 University In-patients Children, adults Urine, pus, wound, blood DDST, PCR-Sequencing K. pneumoniae 183 50 CTX-M-15 (76 %), TEM-104 (19 %), TEM-176 (2 %), SHV-11 (3.2 %)
Tanzania [6] 2003 University In-patients Children, adults Urine, wound, blood DDST, PCR-Sequencing E. coli, Enterobacter spp, others 39 28 TEM (55 %), SHV (64 %), CTX-M (45.4 %)
Tanzania [7] 2010 University Both Children, adults Urine DDST K. pneumoniae, E. coli 270 45 ND
Tanzania [53] 2009 University Both Children, adults Urine, pus, wound, blood DDST K. pneumoniae, Escherichia coli, Acinetobacter spp 377 29 ND
Tanzania [54] 2013 University In-patients Women, neonates Rectal swabs DDST K. pneumoniae, E. coli, Enterobacter spp 113 15 ND
Tanzania [55] 2013 University Both Children Urine DDST K. pneumoniae, E. coli, others 84 44 ND
Tanzania [56] 2012 University Both Children, adults Pus DDST K. pneumoniae, E. coli, others 29 79 ND
Tanzania [36] 2007 University Both Children, adults Urine, pus, blood dPCR-Sequencing K. pneumoniae, E. coli, P. aeruginosa, others 227 35 VIM (12.3 %), OXA-48 (4.9 %), KPC (3.5 %), NDM (3.1 %)
Tanzania [57] 2012 University Both Children, adults Wound DDST Pseudomonas spp, Proteus spp, K. pneumoniae, E. coli 117 35 ND
Tanzania [58] 2011 University Both Children, adults Wound DDST K. pneumoniae, E. coli, others 24 71 ND
Tanzania [59] 2009 University Both Children Blood DDST K. pneumoniae, E. coli, others 72 49 ND
Uganda [10] 2011 Regional Both Children, adults Wound DDST K. pneumoniae, E. coli, others 145 81 ND
Uganda [60] 2014 Regional Both Children, adults Urine, blood, wound, CSFe DDST E. coli, K. pneumoniae, P. mirabilis, others 115 62 ND
Uganda [31] 2012 Regional Both Children, adults Urine, pus, wound, sputum, stool, CSF, vaginal-swabs DDST, PCR-Sequencing K. pneumoniae, E. coli, Salmonella spp, others 484 44 CTX-M (70 %), SHV (34 %) and TEM (47 %)
  1. aBoth, out-and in-patients departments
  2. b DDST double disc synergy test
  3. c ND not determined
  4. d PCR polymerase chain reaction
  5. e CSF cerebrospinal fluid