Association between microbial characteristics and poor outcomes among patients with methicillin-resistant Staphylococcus aureus pneumonia: a retrospective cohort study

Table 2 Adjusted associations for mortality or post-infection length of stay among patients with MRSA pneumonia^a

	30-Day-In-Hospital mortality^b		Post-infection length of stay^c
Microbial characteristics	Hazards ratio (95 % Confidence Interval)	P-value	Odds ratio (95 % Confidence Interval)	P-value
Panton-Valentine leukocidin	0.72 (0.23–2.25)	0.566	0.67 (0.27–1.69)	0.398
SCCmec
Type II	1.66 (0.53–5.16)	0.383	1.77 (0.69–4.52)	0.235
Type IV	0.62 (0.20–1.93)	0.414	0.51 (0.20–1.30)	0.158
agr dysfunction	1.84 (0.54–6.20)	0.323	1.30 (0.42–4.05)	0.648
Arginine catabolic mobile element	0.37 (0.10–1.47)	0.158	0.57 (0.22–1.48)	0.250
Toxic shock syndrome toxin-1	1.24 (0.14–11.10)	0.847	2.86 (0.26–31.18)	0.389
PFGE type
USA100	1.29 (0.42–3.95)	0.656	1.70 (0.67–4.33)	0.268
USA300	0.54 (0.15–1.92)	0.344	0.60 (0.24–1.50)	0.269

IQR interquartile range, SCCmec staphylococcal cassette chromosome mec, agr accessory gene regulator, PFGE pulsed-field gel electrophoresis
^aAdjusted for gender, age, previous hospital admission within 12 months, previous MRSA infection or colonization, positive influenza test, Charlson Comorbidity Index score, and treatment (linezolid or vancomycin)
^bDefined as death occurring within the first 30 days after the day when the first MRSA positive respiratory or blood culture was collected
^c Defined as the day the first MRSA positive respiratory or blood culture was collected until the day the patient was either discharged from the hospital or died

ISSN: 2047-2994