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Table 2 Results of TEWL measurements. Differences between agents (safety population, n = 22)

From: Safety and tolerability of virucidal hand rubs: a randomized, double-blind, cross-over trial with healthy volunteers

Difference to agent

 

P2

P3

R

Agent

Differ-ence

95 %-CI

P

Difference

95 %-CI

P

Difference

95 %-CI

P

 P1

6.16

2.54–9.79

0.0013

6.14

2.38–9.89

0.002

−1.54

−5.33 - 2.26

0.42

 P2

-

-

-

−0.03

−3.69 - 3.64

0.99

−7.70

−11.45 - −2.96

0.0001

 P3

-

-

-

-

-

-

−7.67

−11.45 - − 3.90

0.0002

  1. P1 = Ethanol (100 %) 45 g, 1-Propanol (Ph.Eur.) 18 g (Softa-Man® acute, B. Braun Melsungen AG), P2 = Ethanol (99 %) 95 g (Sterillium® virugard, Bode Chemie Hamburg GmbH), and, P3 = Ethanol (96 %) 57,6 g, 1-Propanol (Ph.Eur.) 10 g (Manorapid® Synergy, Antiseptica GmbH, R (reference product) = Ethanol (100 %) 45 g, 1-Propanol (Ph.Eur.) 18 g (Softa-Man® pure, B. Braun Melsungen AG)
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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