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Table 1 Summary of data on rates of resistant Pseudomonas aeruginosa

From: Clinical and economic consequences of hospital-acquired resistant and multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis

Author (Year)

Country

Setting

Rates of resistance

Ref.

NNIS (2004)

USA

ICU

Imipenem resistance = 15%

[18]

Quinolone resistance = 9%

3rd-generation cephalosporin resistance = 20%

Obritsch et al. (2004)

USA

ICU

MDR P. aeruginosa (defined as resistance to at least three of the following four drugs: imipenem, ceftazidime, ciprofloxacin, and tobramycin) increased from 4% in 1993 to 14% in 2002

[19]

Morrow et al. (2013)

USA

Tertiary

Doripenem resistance = 11.4%

[20]

Imipenem resistance = 21.9%

Meropenem resistance = 15.4%

Levofloxacin resistance = 26.0%

Ceftazidime resistance = 15.2%

Tobramycin resistance = 10.1%

Piperacillin / tazobactam resistance = 14.7%

Souli et al. (2008), European Center for Disease Prevention and Control (2013)

Europe

Tertiary

Carbapenem resistance = > 25%

[21, 22]

De Francesco et al. (2013)

Italy

Tertiary

MDR P. aeruginosa (defined as resistance to 5 commonly prescribed antibiotics) increased from 2.1% in 2007 to 4.1% in 2010

[23]

Joo et al. (2011)

Korea

Tertiary

Ceftazidime resistance = 37%

[24]

Piperacillin resistance = 22%

Imipenem resistance = 23%

Fluoroquinolone resistance = 24%

Aminoglycoside resistance = 18%

Gales et al. (2001)

South America

Tertiary

MDR resistance = 8.2%

[25]

Raja et al. (2001)

Malaysia

Tertiary

MDR resistance = 6.9%

[26]