Table 2 Interrupted time-series regression analysis of the MRSA/MSSA bacteremias (total and ≥48 h), MRSA/MSSA systemic (Hospital - % of admissions) and MRSA/MSSA systemic (Community – total numbers)
Parameter | Unstandardized | Standardized | t | p | 95% CI | D-W | |
|---|---|---|---|---|---|---|---|
Coefficients - B (Std. Error) | Coefficients - β | ||||||
MRSA bacteremias | Constant | 17.40 (1.64) | 10.59 | .000 | 14.04 to 20.75 | 1.573 | |
Pre-intervention trend | -.025 (.181) | -.033 | -.138 | .891 | -.39 to .34 | ||
Post-intervention change | −8.32 (2.072) | -.554 | −4.016 | .000 | −12.55 to −4.09 | ||
Post-intervention trend | -.45 (.221) | -.393 | −2.065 | .048 | -.90 to -.005 | ||
MSSA bacteremias | Constant | 17.36 (2.45) | 7.075 | .000 | 12.35 to 22.37 | 2.068 | |
Pre-intervention trend | .29 (.270) | .604 | 1.098 | .281 | -.255 to .848 | ||
Post-intervention change | −2.28 (3.095) | -.235 | -.737 | .467 | −8.60 to 4.04 | ||
Post-intervention trend | -.61 (.330) | -.818 | −1.858 | .073 | −1.28 to.06 | ||
MRSA ≥48 h bacteremias | Constant | 13.46 (1.38) | 9.75 | .000 | 10.64 to 16.28 | 1.753 | |
Pre-intervention trend | -.10 (.152) | -.168 | -.659 | .515 | -.41 to .21 | ||
Post-intervention change | −6.79 (1.741) | -.577 | −3.901 | .001 | −10.34 to −3.23 | ||
Post-intervention trend | -.19 (.185) | -.216 | −1.060 | .298 | -.57 to .18 | ||
MSSA ≥48 h bacteremias | Constant | 5.96 (1.84) | 3.22 | .003 | 2.16 to 9.76 | 1.901 | |
Pre-intervention trend | .173 (.272) | .503 | .634 | .532 | -.38 to .73 | ||
Post-intervention change | 1.10 (2.112) | .178 | .521 | .606 | −3.24 to 5.44 | ||
Post-intervention trend | -.45 (.298) | -.990 | −1.524 | .140 | −1.06 to .15 | ||
MRSA Systemic (Trust) | Constant | 5.8 (.225) | 25.78 | .000 | 5.34 to 6.26 | 1.599 | |
Pre-intervention trend | -.17 (.028) | -.830 | −6.252 | .000 | -.23 to -.11 | ||
Post-intervention change | −2.03 (.271) | -.506 | −7.493 | .000 | −2.58 to −1.47 | ||
Post-intervention trend | .10 (.033) | .350 | 3.269 | .003 | .040 to 17 | ||
MSSA Systemic (Trust) | Constant | 3.25 (.191) | 17.01 | .000 | 2.86 to 3.64 | 1.421 | |
Pre-intervention trend | -.05 (.024) | -.892 | −2.358 | .026 | -.10 to -.007 | ||
Post-intervention change | .29 (.230) | .248 | 1.289 | .208 | -.17 to .76 | ||
Post-intervention trend | .134 (.028) | 1.477 | 4.846 | .000 | .07 to .19 | ||
MRSA Systemic (GP) | Constant | 287 (12.35) | 23.25 | .000 | 262 to 313 | 1.962 | |
Pre-intervention trend | −2.49 (1.55) | -.285 | −1.602 | .120 | −5.68 to .69 | ||
Post-intervention change | −66.23 (14.89) | -.402 | −4.447 | .000 | −96.73 to −35.72 | ||
Post-intervention trend | −4.22 (1.78) | -.338 | −2.362 | .025 | −7.88 to -.56 | ||
MSSA Systemic (GP) | Constant | 906 (31.57) | 28.71 | .000 | 841 to 971 | 2.427 | |
Pre-intervention trend | −7.52 (3.97) | −1.27 | −1.891 | .069 | −15.67 to .62 | ||
Post-intervention change | 11.71 (38.04) | .105 | .308 | .760 | −66.22 to 89.65 | ||
Post-intervention trend | 10.16 (4.56) | 1.20 | 2.224 | .034 | .80 to 19.51 |