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Table 1 Antibiotic resistance against eight antimicrobial agents, stratified for origin of the sample

From: Antimicrobial susceptibility profiles of human and piglet Clostridium difficile PCR-ribotype 078

 Antibiotic agent

MIC 90(mg/L)

Resistant isolates according to CLSIb(%)

Human n=49

Pig n=50

ECOFFa(mg/L)

Breakpoint (mg/L)

Human n=49

Pig n=50

Difference p-value

Amoxicillin

0.25

0.25

2

16

0 (0%)

0 (0%)

1.00

Cefuroxim

≥256

≥256

-

-

NA

NA

NA

Clindamycin

2

2

≥256

8

3 (6%)

1 (2%)

0.30

Erythromycin

≥256

≥256

≥256

8

29 (59%)

38 (76%)

0.07

Ciprofloxacin

≥32

≥32

≥32

8

46 (94%)

48 (96%)

0.044

Moxifloxacin

8

8

≥64

8

8 (16%)

8 (16%)

0.067

Tetracycline

8

8

8

16

0 (0%)

0 (0%)

1.00

Imipenem

≥32

≥32

8

16

14 (29%)

25 (50%)

0.03

  1. a ECOFF: Epidemiological cut-off value - The European Committee on Antimicrobial Susceptibility Testing (EUCAST).
  2. b CLSI: Clinical and Laboratory Standards Institute.
  3. NA: not applicable. This is stated because no breakpoint was determined by the CLSI and, therefore, the percentage of resistant isolates could not be determined.