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Table 3 Risk factors associated with CVC-associated BSI on NEO-KISS NICUs

From: The impact of staffing on central venous catheter-associated bloodstream infections in preterm neonates – results of nation-wide cohort study in Germany

Parameter

Category

OR

CI 95%

p-value

Realized staffing percentage

Missing

1.25

(0.83-1.88)

0.289

<95%

1.47

(1.11-1.95)

0.008

≥95%

1=reference

  

Birth weight

<500 g

4.23

(2.46-7.3)

<0.001

500-749 g

3.17

(1.85-5.45)

<0.001

750-999 g

2.28

(1.47-3.53)

<0.001

1000-1249 g

1.36

(0.86-2.14)

0.187

1250-1499 g

1=reference

  

Gestational age (completed weeks)

<27 weeks

3.97

(2.23-7.09)

<0.001

27-28 weeks

3.04

(1.79-5.16)

<0.001

29-30 weeks

1.99

(1.05-3.77)

0.035

>30 weeks

1=reference

  

Length of stay

21-34 days

0.44

(0.29-0.69)

0.001

35-48 days

0.32

(0.21-0.49)

<0.001

>48 days

0.29

(0.2-0.42)

<0.001

<21 days

1=reference

  

Standards for indication of hand hygiene

Yes

0.61

(0.44-0.84)

0.002

No

1=reference

  

Daily disinfection of the buttons of the ventilation systems

Yes

0.68

(0.5-0.93)

0.014

No

1=reference

  

Disinfection of the application port before medication infusion/connection of an infusion system

Often

0.48

(0.31-0.77)

0.002

Rarely/no

1=reference

  

Infusion preparation

On ward without laminar-flow bench

1.53

(1.02-2.28)

0.039

In the pharmacy OR on ward with laminar-flow bench

1=reference

  
  1. IQR, inter-quartile range. CI 95%, 95% confidence interval. CVC, central venous catheter. BSI, bloodstream infection. Realized staffing percentage, ratio of realized staffing / planned staffing * 100.
  2. Results of the multivariable regression analysis by GEE models.